74773-19-6

Basic information

• Product Name: 5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione
• Synonyms: 5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione
• CAS NO: 74773-19-6
• Molecular Weight: 342.419
• Mol File: 74773-19-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione(74773-19-6)
• EPA Substance Registry System: 5-{4-[2-(6-methyl-pyridin-2-yl)ethoxy]benzyl}-2,4-thiazolidinedione(74773-19-6)

Safety Data

• Hazardous Substances Data: 74773-19-6(Hazardous Substances Data)

Upstream product

• 136401-66-6 5-<4-<2-(6-Methyl-2-pyridyl)ethoxy>benzylidene>-2,4-thiazolidinedione 
• 85002-84-2 4-[2-(6-methyl-pyridin-2-yl)ethoxy]nitrobenzene 
• 85583-36-4 4-[2-(6-methyl-pyridin-2-yl)ethoxy]aniline 
• 934-78-1 2-(6-methylpyridin-2-yl)-ethanol 
• 350-46-9 4-Fluoronitrobenzene 
• 85003-45-8 methyl 2-chloro-3-<4-<2-(6-methyl-2-pyridyl)ethoxy>phenyl>propionate 
• 17356-08-0 thiourea 

Relevant articles and documents

Pyridine N-oxide compounds which are useful as hypoglycemic and hypolipidemic agents

There is disclosed a novel thiazolidinedione derivative of the general formula (I): STR1 wherein R1 and R2 are the same or different and are a hydrogen atom or a lower alkyl group, or a salt thereof. The thiazolidinedione derivative has hypoglycemic activity and hypolipidemic activity.

Method for producing thiazolidinedione derivatives

A compound of the formula: STR1 (wherein R1 is hydrogen or a lower alkyl) can be produced advantageously by (1) reacting a compound of the formula: STR2 (wherein R1 has a meaning given above) with a halogenating agent or sulfonyl halide to give a compound of the formula: STR3 (wherein R1 has a meaning given above and X is a halogen or an alkyl- or aryl-sulfonyloxy), (2) reacting the resulting compound with a compound of the formula: STR4 to give a compound of the formula: (wherein R1 has the meaning given above), (3) reacting the resulting compound with a compound of the formula: STR5 to give a compound of the formula: STR6 (wherein R1 has the meaning given above), and (4) subjecting the resulting compound to catalytic reduction.