7478-61-7

Basic information

• Product Name: (1E)-1,4-diphenylbutan-1-one oxime
• CAS NO: 7478-61-7
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.3123
• Mol File: 7478-61-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 401.1°C at 760 mmHg
• Flash Point: 257.6°C
• Density: 1.01g/cm³
• Vapor Pressure: 3.73E-07mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: (1E)-1,4-diphenylbutan-1-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-1,4-diphenylbutan-1-one oxime(7478-61-7)
• EPA Substance Registry System: (1E)-1,4-diphenylbutan-1-one oxime(7478-61-7)

Safety Data

• Hazardous Substances Data: 7478-61-7(Hazardous Substances Data)

Usage

General Description

(1E)-1,4-diphenylbutan-1-one oxime, also known as benzophenone oxime, is a chemical compound with the molecular formula C14H15NO. It is commonly used as a photoinitiator in the production of various polymers, such as acrylics and methacrylates. (1E)-1,4-diphenylbutan-1-one oxime is also used as a fragrance ingredient in perfumes and personal care products. Additionally, (1E)-1,4-diphenylbutan-1-one oxime has been studied for its potential antioxidant and anti-inflammatory properties. However, it is important to handle this chemical with care as it can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 5407-91-0 1,4-diphenylbutan-1-one 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 100-47-0 benzonitrile 
• 72256-08-7 1,4-diphenyl-1-pentanone 
• 100-58-3 phenylmagnesium bromide 
• 177756-65-9 N-methoxy-N-methyl-4-phenylbutyramide 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 65-85-0 benzoic acid 

Downstream Products

• 74533-88-3 1,4-diphenylbutan-1-amine 
• 3056-71-1 N-phenyl-4-phenylbutyramide 
• 77334-17-9 O-[3-(N,N-Dimethylamino)propyl]-1,4-diphenyl-1-butanone oxime 

Relevant articles and documents

Zinc-Enabled Annulation of Trifluorodiazoethane with 2 H-Azirines to Construct Trifluoromethyl Pyrazolines, Pyrazoles, and Pyridazines

A diethylzinc-promoted unconventional annulation reaction of 2,2,2-trifluorodiazoethane with 2H-azirines is described. This transformation involves two [3 + 2] cycloaddition steps and one dinitrogen extrusion process in one pot, thus giving a broad array

Iron-Catalyzed, Iminyl Radical-Triggered Cascade 1,5-Hydrogen Atom Transfer/(5+2) or (5+1) Annulation: Oxime as a Five-Atom Assembling Unit

By integration of iminyl radical-triggered 1,5-hydrogen atom transfer and (5+2) or (5+1) annulation processes, a series of structurally novel and interesting azepine and spiro-tetrahydropyridine derivatives have been successfully prepared in moderate to good yields. This method utilizes FeCl2 as the catalyst and readily available oximes as five-atom units, while showcasing broad substrate scope and good functional group compatibility. The annulation products can be easily converted into many valuable compounds. Moreover, DFT calculation studies are performed to provide some insights into the possible reaction mechanisms for the (5+2) and (5+1) annulations.

Novel intramolecular reactivity of oximes: Synthesis of cyclic and spiro-fused imines

(Chemical Equation Presented) Under conventional heat (135-145°C) or microwave irradiation and 1 equiv of acetic anhydride, ortho-substituted aryl-oximes undergo a novel sp3 C-H activated cyclization to produce the corresponding isoindoles, and