74793-33-2Relevant articles and documents
OMEGA-3 FATTY ACID PRODRUG COMPOUNDS AND USES THEREOF
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Page/Page column 23, (2016/09/22)
Provided herein are prodrug compounds, their preparation and their uses, such as treating liver diseases or non-liver diseases via intervening in the molecular pathways in the liver. Novel prodrug compounds of eicosapentaenoic and docosahexaenoic acids, t
Synthesis of spiro C-arylglycoriboside via Pd(II)-catalyzed spirocyclization
Awasaguchi, Ken-Ichiro,Miyazawa, Masahiro,Uoya, Ikuyo,Inoue, Koichi,Nakamura, Koji,Yokoyama, Hajime,Kakuda, Hiroko,Hirai, Yoshiro
experimental part, p. 2392 - 2396 (2010/12/18)
Spiro C-arylglycoriboside was synthesized in 21 steps via Pd(II)-catalyzed spirocyclization as a key reaction. Hemiketal was obtained in 47% overall yield from cis-2-butene-1,4-diol and spirocyclized with PdCl2(PhCN) 2 in dilute THF solution (0.01 M) to afford the 1,6-dioxaspiro[4.4] nonane skeleton in high yield. The spirocyclo adduct was transformed into spiro C-arylglycoriboside in five steps. Georg Thieme Verlag Stuttgart New York.
A novel method for the synthesis of 4'-thiopyrimidine nucleosides using hypervalent iodine compounds.
Nishizono, Naozumi,Baba, Ryosuke,Nakamura, Chika,Oda, Kazuaki,Machida, Minoru
, p. 3692 - 3697 (2007/10/03)
The coupling reactions of cyclic sulfides with a silylated pyrimidine nucleobase using a hypervalent iodine reagent were investigated. The reaction of silylated uracil with cyclic sulfide 12 using PhI=O gave the desired beta-anomer 14 in moderate yield. 4
