74796-19-3Relevant articles and documents
Intramolecular Cycloaddition of (Allylimino)ketens: Access to 3-Azabicyclohept-2-en-7-ones
Maujean, Alain,Marcy, Guy,Chuche, Josselin
, p. 92 - 93 (1980)
Pyrolysis of the enamino esters (1a, b) leads to the (allylimino)keten intermediates (2a, b) which by cycloaddition and 1,5-sigmatropic hydrogen shift are converted into the new bicyclic heterocycles (3a, b), respectively, and, via the azatrienals (5), to
Tandem vinyl radical Minisci-type annulation on pyridines: one-pot expeditious access to azaindenones
Xia, Dong,Duan, Xin-Fang
supporting information, p. 13570 - 13573 (2021/12/23)
A new regiospecific alkylative/alkenylative cascade annulation of pyridines has been achieved whilst the corresponding classic Minisci alkylative annulation failed. This protocol provides a novel and expeditious access to azaindenones and related compoundsviacross-dehydrogenative coupling with the long-standing problem of C2/C4 regioselectivity of pyridines being well addressed.
FIBROBLAST GROWTH FACTOR 23 ANTAGONISTS AND RELATED COMPOSITIONS AND METHODS
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Page/Page column 25-26; 33, (2019/05/15)
This disclosure relates to small molecule inhibitors of Fibroblast growth factor 23 (FGF-23) and related compositions and methods of treatment.
