748124-46-1

Basic information

• Product Name: 3,4-Difluoro-N-methylbenzenemethanamine
• Synonyms: Benzenemethanamine, 3,4-difluoro-N-methyl- (9CI);Benzenemethanamine, 3,4-difluoro-N-methyl;(3,4-Difluorophenyl)methyl](methyl)amine;3,4-Difluoro-N-methylbenzenemethanamine;3,4-Difluoro-N-Methyl-benzylaMine;1-(3,4-Difluorophenyl)-N-methylmethanamine
• CAS NO: 748124-46-1
• Molecular Formula: C₈H₉F₂N
• Molecular Weight: 157.16
• Product Categories: HALIDE
• Mol File: 748124-46-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 176.12°C at 760 mmHg
• Flash Point: 60.315°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 1.11mmHg at 25°C
• Refractive Index: 1.477
• CAS DataBase Reference: 3,4-Difluoro-N-methylbenzenemethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Difluoro-N-methylbenzenemethanamine(748124-46-1)
• EPA Substance Registry System: 3,4-Difluoro-N-methylbenzenemethanamine(748124-46-1)

Safety Data

• Hazardous Substances Data: 748124-46-1(Hazardous Substances Data)

Usage

General Description

3,4-Difluoro-N-methylbenzenemethanamine is a chemical compound with the molecular formula C8H9F2N. It is a derivative of N-methylbenzenemethanamine, with two fluorine atoms attached to the 3 and 4 positions of the benzene ring. 3,4-Difluoro-N-methylbenzenemethanamine is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It may also have potential applications in the development of new drugs or agrochemicals. Its chemical properties and reactivity make it a valuable reagent in chemical research and development. However, as with any chemical, proper handling and safety precautions should be observed when working with 3,4-Difluoro-N-methylbenzenemethanamine to avoid any potential hazards.

InChI:InChI=1/C8H9F2N/c1-11-5-6-2-3-7(9)8(10)4-6/h2-4,11H,5H2,1H3

Upstream product

• 1441345-18-1 tert-butyl 3,4-difluorobenzylcarbamate 
• 72235-53-1 3,4-difluorobenzylamine 
• 74-89-5 methylamine 
• 85118-01-0 alpha-bromo-3,4-difluorotoluene 

Downstream Products

• 957113-02-9 C₃₄H₄₂F₃N₃O₆ 
• 1001192-54-6 5-[N-(3,4-difluorobenzyl)-N-methylaminocarbonyl]-3-(3-methylbenzyl)-6-hydroxy-1H-indazole 

Relevant articles and documents

PYRIMIDO[5,4-d]PYRIMIDINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS

The present invention relates to pyrimido[5,4-d]pyrimidine derivatives of formula (I), including pharmaceutically acceptable salts and solvates thereof. Compounds of the invention are inhibitors of ENT family transporter, especially of ENT1, and are useful as therapeutic compounds for the treatment of cancers. The invention also relates to the combined use of the pyrimido[5,4-d]pyrimidine derivatives with an adenosine receptor antagonist, for the treatment of cancers.