7496-56-2

Basic information

• Product Name: 4-benzyl-1,3-thiazol-2-amine
• Synonyms: 4-benzyl-1,3-thiazol-2-amine;4-benzyl-1,3-thiazol-2-amine(SALTDATA: FREE);4-benzylthiazol-2-amine;4-Benzyl-thiazol-2-ylamine
• CAS NO: 7496-56-2
• Molecular Formula: C₁₀H₁₀N₂S
• Molecular Weight: 190.27
• Mol File: 7496-56-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 349.5°Cat760mmHg
• Flash Point: 165.2°C
• Appearance: /
• Density: 1.236g/cm³
• Vapor Pressure: 4.68E-05mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 4-benzyl-1,3-thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyl-1,3-thiazol-2-amine(7496-56-2)
• EPA Substance Registry System: 4-benzyl-1,3-thiazol-2-amine(7496-56-2)

Safety Data

• Hazardous Substances Data: 7496-56-2(Hazardous Substances Data)

Usage

General Description

4-Benzyl-1,3-thiazol-2-amine is a chemical compound with the molecular formula C11H10N2S. It is a thiazole derivative that consists of a thiazole ring with a benzyl group and an amino group attached at the 2 and 4 positions, respectively. 4-benzyl-1,3-thiazol-2-amine is used in the synthesis and development of pharmaceutical drugs and bioactive molecules. It has been studied for its potential biological activities, including its antiproliferative and cytotoxic effects on cancer cells. 4-Benzyl-1,3-thiazol-2-amine has the potential to be used in the pharmaceutical industry for the development of new drugs with therapeutic applications.

InChI:InChI=1/C10H10N2S/c11-10-12-9(7-13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,11,12)

Upstream product

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Downstream Products

• 121953-41-1 4-benzyl-2-imino-3-methyl-2,3-dihydrothiazole 
• 121953-29-5 4-benzyl-3-methyl-2-trifluoroacetylimino-2,3-dihydrothiazole 
• 121953-09-1 4-benzyl-3-p-bromophenacyl-2-imino-2,3-dihydrothiazole 
• 121953-16-0 4-benzyl-3-p-bromophenacyl-2-trifluoroacetylimino-2,3-dihydrothiazole 

Relevant articles and documents

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MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF

Formulations and methods for reducing blood glucose and/or increasing insulin signaling in a subject have been developed. The formulations include SBI-477 and compounds based on SBI-477 i.e., SBI-477 analogs (collectively, SBI-477 compounds) and/or Mondo family inhibitors, in an effective amount to inhibit intracellular lipid accumulation and/or increase cellular glucose uptake when compared to levels in a control subject not administered the composition. Also disclosed are methods of reducing intracellular lipid accumulation and/or increase glucose uptake in a subject in need thereof. The method includes administering to the subject an effective amount of SBI-477 compounds and/or Mondo family inhibitor to reducing intracellular lipid accumulation and/or increase glucose uptake in the subject. Also disclosed are method for treating one or more Myc-driven cancers, including neuroblastoma, lung squamous cell carcinoma/lung adenocarcinoma, liver hepatocellular carcinoma, colon adenocarcinoma, acute myeloid leukemia, and breast invasive carcinoma.

MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF

Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including inflammatory and immune diseases, having the structure of formula (I): an en