7496-82-4

Basic information

• Product Name: 2-(4-METHOXY-PHENYL)-INDOLIZINE
• Synonyms: 2-(4-METHOXY-PHENYL)-INDOLIZINE
• CAS NO: 7496-82-4
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.27
• Mol File: 7496-82-4.mol
• Article Data: 14

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.08g/cm³
• Refractive Index: 1.59
• CAS DataBase Reference: 2-(4-METHOXY-PHENYL)-INDOLIZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXY-PHENYL)-INDOLIZINE(7496-82-4)
• EPA Substance Registry System: 2-(4-METHOXY-PHENYL)-INDOLIZINE(7496-82-4)

Safety Data

• Hazardous Substances Data: 7496-82-4(Hazardous Substances Data)

Usage

General Description

2-(4-Methoxy-phenyl)-indolizine is a chemical compound with the molecular formula C16H13NO. It is a derivative of indolizine, a five-membered heterocyclic ring containing one nitrogen atom. 2-(4-METHOXY-PHENYL)-INDOLIZINE has a 4-methoxyphenyl group attached to the indolizine ring. It is a yellowish crystalline solid that is insoluble in water but soluble in organic solvents. 2-(4-Methoxy-phenyl)-indolizine has potential applications in the field of organic synthesis, pharmaceuticals, and materials science. Its unique structure and properties make it a promising candidate for further research and development in various scientific and industrial disciplines.

InChI:InChI=1/C15H13NO/c1-17-15-7-5-12(6-8-15)13-10-14-4-2-3-9-16(14)11-13/h2-11H,1H3

Upstream product

• 109-06-8 α-picoline 
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• 5469-11-4 p-methoxyphenacyl-α-picolinium iodide 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 77823-63-3 (3,5-Dibromo-4-hydroxy-phenyl)-[2-(4-methoxy-phenyl)-indolizin-3-yl]-methanone 
• 7496-41-5 2-(4-hydroxyphenyl)indolizine 
• 96866-66-9 2-(4-methoxyphenyl)octahydroindolizine 
• 345941-11-9 (3-Bromo-4-hydroxy-phenyl)-[2-(4-methoxy-phenyl)-indolizin-3-yl]-methanone 
• 79285-93-1 [3-Bromo-4-(3-dibutylamino-propoxy)-phenyl]-[2-(4-methoxy-phenyl)-indolizin-3-yl]-methanone; compound with oxalic acid 
• 101624-26-4 2-(4-methoxyphenyl)-3-indolizine carboxaldehyde 
• 1210434-92-6 2-(4-methoxyphenyl)-3-(4,6-dinitro-2,1,3-benzoxadiazol-7-yl)indolizine 
• 1210435-02-1 C₂₁H₁₃N₅O₇ 
• 1603829-36-2 5-(4-chlorophenyl)-2-(4-methoxyphenyl)indolizine 
• 1603829-37-3 2-(4-methoxyphenyl)-5-(4-nitrophenyl)indolizine 

Relevant articles and documents

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

Mechanochemical Synthesis of 1,2-Diketoindolizine Derivatives from Indolizines and Epoxides Using Piezoelectric Materials

A simple and efficient mechanochemical-induced approach for the synthesis of 1,2-diketoindolizine derivatives has been developed. BaTiO3 was used as the piezoelectric material in this transformation. This method features no usage of solvent, simple experimental operation, scalable potential, and high conversion efficiency, which make it attractive and practical.

NH4I-catalyzed C–S bond formation via an oxidation relay strategy: Efficient access to dithioether decorated indolizines

An efficient NH4I-catalyzed C–H/S–H cross-coupling reaction of indolizines with thiols is reported. Compared to previous methods, this environmentally friendly oxidation relay strategy uses O2 as an oxidant to afford dithioether decorated indolizines in up to 98% yield. Promising results have been obtained, indicating the high applicability and atom economy of this method.