74979-74-1

Basic information

• Product Name: diethyl-1,4-bis(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: diethyl-1,4-bis(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS NO: 74979-74-1
• Molecular Weight: 465.546
• Mol File: 74979-74-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl-1,4-bis(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl-1,4-bis(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(74979-74-1)
• EPA Substance Registry System: diethyl-1,4-bis(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate(74979-74-1)

Safety Data

• Hazardous Substances Data: 74979-74-1(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 104-94-9 4-methoxy-aniline 
• 33240-23-2 ethyl (Z)-3-(4-methoxyanilino)-2-butenoate 
• 140445-85-8 N-[chloro(4-methoxyphenyl)methyl]pyridinium chloride 

Relevant articles and documents

Synthesis and 3D-QSAR study of 1,4-dihydropyridine derivatives as MDR cancer reverters

A series of symmetrical and unsymmetrical 1,4-dihydropyridines were synthesized by a rapid, single pot microwave irradiation (MWI) based protocol along with conventional approach and characterized by NMR, IR and mass spectroscopic techniques. The compound

1-ARYL- AND 1-BENZYL-3,5-DIETHOXYCARBONYL-1,4-DIHYDROPYRIDINES

The possibility has been studied of using anilines in the Hantzsch synthesis.It has been shown that, with the exception of those containing strong electron-accepting substituents, they take part in this reaction with the formation of 1-aryl-1,4-dihydropyridines.The reaction largely depends on the nature of the substituents in the aniline and in the benzaldehyde and is promoted by electron-accepting substituents in the aldehyde and electron-donating substituents in the amine.The mechanism of the reaction is discussed.A number of 1-benzyl-1,4-dihydroxypyridines have been synthesized.The UV, IR, and PMR spectra and the electro-oxidation of the compounds obtained have been studied.