7499-69-6 Usage
Description
(3-nitrophenyl)(thiophen-2-yl)methanone is a chemical compound with the molecular formula C12H8N2O3S. It is a yellow solid that is used in organic synthesis as a building block for more complex compounds. (3-nitrophenyl)(thiophen-2-yl)methanone contains a nitro group, a phenyl group, a thiophene group, and a ketone group. It is important to handle this compound with care, as it can be harmful if it comes into contact with the skin, eyes, or is ingested. It should be stored in a cool, dry, well-ventilated area and away from any sources of ignition. Overall, (3-nitrophenyl)(thiophen-2-yl)methanone is a versatile compound that is used in various chemical reactions for the production of other organic compounds.
Uses
Used in Organic Synthesis:
(3-nitrophenyl)(thiophen-2-yl)methanone is used as a building block for the synthesis of more complex organic compounds. Its unique structure, containing a nitro group, a phenyl group, a thiophene group, and a ketone group, allows it to participate in various chemical reactions, making it a valuable component in the creation of new molecules.
Used in Chemical Research:
(3-nitrophenyl)(thiophen-2-yl)methanone is also used in chemical research to study the properties and reactions of different functional groups. Its presence in a molecule can provide insights into the reactivity and stability of various chemical bonds, contributing to the advancement of knowledge in organic chemistry.
Used in Pharmaceutical Industry:
(3-nitrophenyl)(thiophen-2-yl)methanone can be used as an intermediate in the synthesis of pharmaceutical compounds. Its ability to participate in various chemical reactions makes it a useful component in the development of new drugs and medications.
Used in Material Science:
(3-nitrophenyl)(thiophen-2-yl)methanone can be used in the development of new materials with specific properties. Its unique structure can contribute to the creation of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, making it valuable in material science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7499-69-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,9 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7499-69:
(6*7)+(5*4)+(4*9)+(3*9)+(2*6)+(1*9)=146
146 % 10 = 6
So 7499-69-6 is a valid CAS Registry Number.
7499-69-6Relevant articles and documents
Efficient Access to Chiral Benzhydrols via Asymmetric Transfer Hydrogenation of Unsymmetrical Benzophenones with Bifunctional Oxo-Tethered Ruthenium Catalysts
Touge, Taichiro,Nara, Hideki,Fujiwhara, Mitsuhiko,Kayaki, Yoshihito,Ikariya, Takao
supporting information, p. 10084 - 10087 (2016/09/03)
A concise asymmetric transfer hydrogenation of diaryl ketones, promoted by bifunctional Ru complexes with an etherial linkage between 1,2-diphenylethylenediamine (DPEN) and η6-arene ligands, was successfully developed. Because of the effective discrimination of substituents at the ortho position on the aryl group, unsymmetrical benzophenones were smoothly reduced in a 5:2 mixture of formic acid and triethylamine with an unprecedented level of excellent enantioselectivity. For the non-ortho-substituted benzophenones, the oxo-tethered catalyst electronically discerned biased substrates, resulting in attractive performance yielding chiral diarylmethanols with >99% ee.
Benzylation via Tandem Grignard Reaction - Iodotrimethylsilane (TMSI) Mediated Reduction
Stoner, Eric J.,Cothron, Darlene A.,Balmer, Mary K.,Roden, Brian A.
, p. 11043 - 11062 (2007/10/02)
A method has been developed which allows for the large scale preparation of biarylmethanes.This method involves the initial formation of biarylmethanols via reaction of aryl Grignards with carbonyl compounds followed by a subsequent reduction with iodotrimethylsilane (TMSI).A number of improvements over existing literature procedures are reported as well as previously unobserved dimerizations.Studies reveal that as few as 3 equiv of TMSI will give complete reduction in most cases where either of the substituents are not heteroaromatic.Mono-substituted alkanols react with TMSI to afford the corresponding iodides.A mechanistic study of the TMSI reduction is also reported.
