749921-32-2

Basic information

• Product Name: methyl 3-(4-trifluoromethylphenylamino)-2-pentenoate
• Synonyms: methyl 3-(4-trifluoromethylphenylamino)-2-pentenoate
• CAS NO: 749921-32-2
• Molecular Weight: 273.255
• Mol File: 749921-32-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-(4-trifluoromethylphenylamino)-2-pentenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-trifluoromethylphenylamino)-2-pentenoate(749921-32-2)
• EPA Substance Registry System: methyl 3-(4-trifluoromethylphenylamino)-2-pentenoate(749921-32-2)

Safety Data

• Hazardous Substances Data: 749921-32-2(Hazardous Substances Data)

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 30414-53-0 methyl propanoyl acetate 

Downstream Products

• 749921-33-3 3-(4-trifluoromethyl-phenylamino)-pentanoic acid methyl ester 
• 135015-69-9 2-Ethyl-6-trifluoromethyl-4-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methoxy]quinoline hydrochloride 

Relevant articles and documents

METHOD FOR PRODUCING AN OPTICALLY ACTIVE TETRAHYDROQUINOLINE

The present invention provides an industrially advantageous production method of optically active tetrahydroquinolines of formula (1), which comprises: 1) a step of reacting a β-ketoester of formula (2) with an amine of formula (3) to produce an enaminoester of formula (4); 2) a step of subjecting the enaminoester of formula (4) above obtained in 1) to asymmetric hydrogenation to produce an optically active β-amino acid derivative of formula (5); 3) a step of amidating the optically active β-amino acid derivative (5) above obtained in 2) to produce an amide of formula (6); 4) step of alkoxycarbonylating the amide of formula (6) above obtained in 3) to produce a compound of formula (7); and 5) a step of subjecting the compound of formula (7) above to cyclization to produce the optically active tetrahydroquinoline of formula (1).