75003-47-3

Basic information

• Product Name: 5-Quinolin-2-yl-2-thioxo-3-o-tolyl-thiazolidin-4-one
• CAS NO: 75003-47-3
• Molecular Weight: 350.465
• Mol File: 75003-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Quinolin-2-yl-2-thioxo-3-o-tolyl-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Quinolin-2-yl-2-thioxo-3-o-tolyl-thiazolidin-4-one(75003-47-3)
• EPA Substance Registry System: 5-Quinolin-2-yl-2-thioxo-3-o-tolyl-thiazolidin-4-one(75003-47-3)

Safety Data

• Hazardous Substances Data: 75003-47-3(Hazardous Substances Data)

Upstream product

• 1613-37-2 Quinoline N-oxide 
• 23522-37-4 3-(2-methylphenyl)-2-thioxothiazolidin-4-one 

Relevant articles and documents

Studies on Tertiary Amine Oxides. LXVII. Reactions of Aromatic N-Oxides with 3-Arylrhodanines in the Presence of Acetic Anhydride

Quinoline 1-oxides 1 readily react with 3-arylrhodanines 2 in the presence of acetic anhydride to afford 3-aryl-5-(2-quinolyl)rhodanines 3 in high yields.These products resist hydrolysis under both alkaline and acidic conditions, but are oxidized to quinaldinic acid 1-oxide 4 with 30percent hydrogen peroxide in hot acetic acid.Besides isoquinoline 2-oxide 5, pyridine 1-oxide 7a also react in the same way to give 3-aryl-5-(2-pyridyl)rhodanines 8, although the reactivity of γ-picoline 1-oxide 7b is considerably lower.Contrary to 3, 3-phenyl-5-(2-pyridyl)rhodanine 8a is successfully hydrolyzed with boiling 48percent hydrobromic acid to 2-pyridinemethanethiol 10 in 57percent yield.