75040-58-3

Basic information

• Product Name: butyl (Z)-4⁽⁵⁾-(6-carboxyhex-1-enyl)imidazole-5⁽⁴⁾-carboxylate
• CAS NO: 75040-58-3
• Molecular Weight: 294.351
• Mol File: 75040-58-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: butyl (Z)-4⁽⁵⁾-(6-carboxyhex-1-enyl)imidazole-5⁽⁴⁾-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: butyl (Z)-4⁽⁵⁾-(6-carboxyhex-1-enyl)imidazole-5⁽⁴⁾-carboxylate(75040-58-3)
• EPA Substance Registry System: butyl (Z)-4⁽⁵⁾-(6-carboxyhex-1-enyl)imidazole-5⁽⁴⁾-carboxylate(75040-58-3)

Safety Data

• Hazardous Substances Data: 75040-58-3(Hazardous Substances Data)

Upstream product

• 50889-29-7 (5-carboxypentyl)triphenylphosphonium bromide 
• 75040-54-9 butyl 4⁽⁵⁾-formylimidazole-5⁽⁴⁾-carboxylate 

Relevant articles and documents

Heterocyclic Prostaglandin Analogues. Part 2. Hydantoins and Other Imidazole Analogues

The stable hydantoin prostaglandin analogues (2b) and (3b) have been synthesised as racemic compounds.The less polar diastereoisomer of (2b) is a potent inhibitor of platelet aggregation in human platelet-rich plasma and its cyclohexyl analogue (22, R = C6H11) has ca. 14 times the potency of prostaglandin E1 in this test coupled with selectivity of biological action.Other structural modifications such as introduction of a 15-methyl group and insertion of the m-phenylene or m-oxaphenylene moieties into the acid side-chain of (2b) led to a reduction in anti-aggregatory potency.Synthesis of the imidazole (41) is described.