7508-80-7

Basic information

• Product Name: 4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97%
• Synonyms: 4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97%
• CAS NO: 7508-80-7
• Molecular Formula: C₁₄H₁₂ClNO₂
• Molecular Weight: 261.70358
• Mol File: 7508-80-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 326.2°C at 760 mmHg
• Flash Point: 151.1°C
• Appearance: /
• Density: 1.281g/cm³
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97%(7508-80-7)
• EPA Substance Registry System: 4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97%(7508-80-7)

Safety Data

• Hazardous Substances Data: 7508-80-7(Hazardous Substances Data)

Usage

General Description

4-Chloro-N-(2-Methoxyphenyl)benzaMide, 97% is a chemical compound with a purity of 97%. It is an organic compound that consists of a benzene ring with a chlorine atom and a methoxy group attached to it. It is commonly used in research and chemical synthesis as a building block for the production of various pharmaceuticals and agrochemicals. This chemical has a wide range of applications and can be utilized as an intermediate in the manufacturing of various drugs and other organic compounds. Additionally, it is important to handle this chemical with care and in accordance with proper safety protocols due to its potential hazards.

InChI:InChI=1/C14H12ClNO2/c1-18-13-5-3-2-4-12(13)16-14(17)10-6-8-11(15)9-7-10/h2-9H,1H3,(H,16,17)

Upstream product

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Relevant articles and documents

Discovery, Optimization, and Biological Evaluation of Sulfonamidoacetamides as an Inducer of Axon Regeneration

Axon regeneration after injury in the central nervous system is hampered in part because if an age-dependent decline in the intrinsic axon growth potential, and one of the strategies to stimulate axon growth in injured neurons involves pharmacological manipulation of implicated signaling pathways. Here we report phenotypic cell-based screen of chemical libraries and structure-activity-guided optimization that resulted in the identification of compound 7p which promotes neurite outgrowth of cultured primary neurons derived from the hippocampus, cerebral cortex, and retina. In an animal model of optic nerve injury, compound 7p was shown to induce growth of GAP-43 positive axons, indicating that the in vitro neurite outgrowth activity of compound 7p translates into stimulation of axon regeneration in vivo. Further optimization of compound 7p and elucidation of the mechanisms by which it elicits axon regeneration in vivo will provide a rational basis for future efforts to enhance treatment strategies.