7509-61-7Relevant articles and documents
Palladium(II)/N-Heterocyclic Carbene Catalyzed One-Pot Sequential α-Arylation/Alkylation: Access to 3,3-Disubstituted Oxindoles
Reddy Panyam, Pradeep Kumar,Ugale, Bharat,Gandhi, Thirumanavelan
supporting information, p. 7622 - 7632 (2018/06/22)
Rationally designed fluorene-based mono- and bimetallic Pd-PEPPSI complexes were synthesized and demonstrated to be effective for the one-pot sequential α-arylation/alkylation of oxindoles. This streamlined approach offers efficient access to functionalized 3,3-disubstituted oxindoles in excellent yields (up to 89%) under mild reaction conditions.
Methods and Compositions for Selectin Inhibition
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Page/Page column 22, (2008/12/04)
The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selecting. Methods for treating or preventing selectin-mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.
Condensed bridgehead nitrogen heterocyclic systems: Synthesis and antimicrobial activity of thiazolo[3′, 2′: 2, 3]-as-triazino[5, 6-b]indoles and isomeric thiazolo[2′, 3′: 3, 4]-as-triazino[5, 6-b]indoles
Mohan, Jag,Anupama
, p. 628 - 630 (2007/10/03)
2, 3-Dihydro-6-ethyl-5H-as-triazino[5, 6-b]indole-3-thione 4 on condensation with α-haloketone gives 3-aroylmethylthio-6-ethyl-5H-as-triazino[5, 6-b]indolehydrobromide 5 which on PPA catalyzed cyclization furnishes 3-aryl-9-ethylthiazolo[3′, 2′: 2, 3]-as-