7509-65-1

Basic information

• Product Name: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline
• Synonyms: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline;3-(5-methylbenzo[d]oxazol-2-yl)aniline
• CAS NO: 7509-65-1
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.25788
• Mol File: 7509-65-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 389.7°Cat760mmHg
• Flash Point: 189.5°C
• Appearance: /
• Density: 1.222g/cm³
• Vapor Pressure: 2.79E-06mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline(7509-65-1)
• EPA Substance Registry System: 3-(5-methyl-1,3-benzoxazol-2-yl)aniline(7509-65-1)

Safety Data

• Hazardous Substances Data: 7509-65-1(Hazardous Substances Data)

Usage

General Description

3-(5-methyl-1,3-benzoxazol-2-yl)aniline is a chemical compound that belongs to the class of benzoxazole derivatives. It is comprised of a benzoxazole ring with a 5-methyl substitution and an aniline group attached to the third position of the benzoxazole ring. 3-(5-methyl-1,3-benzoxazol-2-yl)aniline has potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. It may possess interesting biological and pharmacological activities due to its structural features, making it a potential candidate for drug discovery and development. Additionally, it may also have uses in the production of dyes, pigments, and other industrial applications due to its aromatic nature and potential for modification.

InChI:InChI=1/C14H12N2O/c1-9-5-6-13-12(7-9)16-14(17-13)10-3-2-4-11(15)8-10/h2-8H,15H2,1H3

Upstream product

• 25284-11-1 5-methyl-2-(3-nitro-phenyl)-benzooxazole 
• 121-90-4 m-nitrobenzoic acid chloride 
• 121-92-6 3-nitrobenzoic acid 
• 351980-74-0 N-(2-hydroxy-5-methyl-phenyl)-3-nitro-benzamide 
• 119-33-5 4-methyl-2-nitrophenol 
• 99-05-8 meta-aminobenzoic acid 
• 95-84-1 3-amino-4-hydroxytoluene 

Relevant articles and documents

Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y14R antagonists with anti-gout potential

The P2Y14 nucleotide receptor, a subtype of P2Y receptors, is implicated in many human inflammatory diseases. Based on the identification of favorable residues of two screening hits in the almost symmetrical P2Y14 binding domain, we

Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition

Structure based virtual screening attempts to discover DUSP1 inhibitors have yielded a scaffold featuring benzoxazole and acylthiourea pharmacophore. A series of its analogues were synthesized to explore structure activity relationship (SAR) of DUSP1 inhi

Benzoxazole derivative as well as preparation method and application of benzoxazole derivative

The invention provides a benzoxazole derivative as well as a preparation method and application of the benzoxazole derivative. The benzoxazole derivative is 5-methylbenzoxazole-2-phenyl-benzamide andhas a structural formula as follows: formula (shown in t