75092-34-1

Basic information

• Product Name: 4-Iodo-1-methyl-3-nitro-1H-pyrazole
• Synonyms: 4-Iodo-1-methyl-3-nitro-1H-pyrazole;4-iodo-1-methyl-3-nitropyrazole;4-iodo-1-methyl-3-nitro-pyrazole
• CAS NO: 75092-34-1
• Molecular Formula: C₄H₄IN₃O₂
• Molecular Weight: 252.99793
• Mol File: 75092-34-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Iodo-1-methyl-3-nitro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodo-1-methyl-3-nitro-1H-pyrazole(75092-34-1)
• EPA Substance Registry System: 4-Iodo-1-methyl-3-nitro-1H-pyrazole(75092-34-1)

Safety Data

• Hazardous Substances Data: 75092-34-1(Hazardous Substances Data)

Upstream product

• 54210-32-1 1-methyl-3-nitro-1H-pyrazole 

Downstream Products

• 66296-67-1 1-methyl-3,4-dinitropyrazole 
• 1904-31-0 methyl-1 amino-3 pyrazole 

Relevant articles and documents

Efficient iodination of structurally varying pyrazoles in heterophase medium

A synthesis of 4-iodo-substituted pyrazoles by iodination of pyrazole and its derivatives in the heterophase (H2O/CHCl3 (CCl 4)) medium with the system KI-KIO3 in the presence of H2SO4 additives was accomplished. The yields of 4-iodo-substituted pyrazoles in the iodination of pyrazole, 3,5- dimethylpyrazole, pyrazole-3(5)-carboxylic acid, 1-methylpyrazole-3-carboxylic acid, 1-methylpyrazole-5-carboxylic acid, 3-nitropyrazole, 1-methyl-3- nitropyrazole, 1-methylpyrazole, 1-ethylpyrazole, and 1-isopropylpyrazole were within 80-97%, whereas in the case of 3-nitropyrazole-5-carboxylic acid it was 32%.

Synthesis of vicinal aminoiodo- and (acetylamino)iodo-1-alkylpyrazoles

3- and 5-(Acetylamino)-4-iodo-1-alkylpyrazoles were obtained by successive acylation and iodination from 3- and 5-amino-1-alkylpyrazoles without isolating intermediate (acetylamino)pyrazoles. 3- and 5-Iodo- and 3,5-diiodo-4-amino-1-methylpyrazoles were synthesized from appropriate iodonitropyrazoles by reduction with SnCl2 in HCl.