75116-28-8Relevant articles and documents
Aerobic Acylarylation of α,β-Unsaturated Amides with Aldehydes
Biswas, Promita,Mandal, Subhasis,Guin, Joyram
supporting information, p. 4294 - 4299 (2020/06/08)
Herein, we illustrate that molecular oxygen (O2) is capable of promoting oxidative radical acylarylation of olefins with aliphatic aldehydes to afford acylated oxindoles in good yield (up to 97%). The key aspect of the process is the utilization of aldehyde auto-oxidation in developing aerobic radical olefin acylarylation. Kinetic studies confirm a lag phase for the reaction. Synthetic utility of the method is apparent via the preparation of biologically potent spirocyclic oxindoles and tetrahydrofuranoindolines.
Visible-Light-Mediated Photocatalytic Difunctionalization of Olefins by Radical Acylarylation and Tandem Acylation/Semipinacol Rearrangement
Bergonzini, Giulia,Cassani, Carlo,Lorimer-Olsson, Haldor,H?rberg, Johanna,Wallentin, Carl-Johan
supporting information, p. 3292 - 3295 (2016/03/05)
A novel method for the mild photoredox-mediated tandem radical acylarylation and tandem acylation/semipinacol rearrangement has been developed. The synthesis of highly functionalized ketones bearing all-carbon α- or β-quaternary centers has been achieved
Acyl Radicals from Aromatic Carboxylic Acids by Means of Visible-Light Photoredox Catalysis
Bergonzini, Giulia,Cassani, Carlo,Wallentin, Carl-Johan
supporting information, p. 14066 - 14069 (2016/01/25)
Simple and abundant carboxylic acids have been used as acyl radical precursor by means of visible-light photoredox catalysis. By the transient generation of a reactive anhydride intermediate, this redox-neutral approach offers a mild and rapid entry to hi
