75198-33-3

Basic information

• Product Name: 1-benzyl-2,4-dichlorobenzene
• Synonyms: 1-benzyl-2,4-dichlorobenzene
• CAS NO: 75198-33-3
• Molecular Weight: 237.128
• Mol File: 75198-33-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2,4-dichlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2,4-dichlorobenzene(75198-33-3)
• EPA Substance Registry System: 1-benzyl-2,4-dichlorobenzene(75198-33-3)

Safety Data

• Hazardous Substances Data: 75198-33-3(Hazardous Substances Data)

Upstream product

• 29334-23-4 2,4-dichloro-α-phenylbenzenemethanol 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 1777-82-8 (2,4-dichlorophenyl)methanol 
• 71-43-2 benzene 
• 4426-21-5 oxybis(diphenylborane) 
• 1747-47-3 2,4-Dichlor-1--benzol 

Downstream Products

• 19811-05-3 2,4-dichlorobenzophenone 

Relevant articles and documents

Ethers as hydrogen sources in BF3·OEt2 promoted reduction of diphenylmethyl alcohols, ethers and esters to hydrocarbons

A novel ether/BF3 reductive system has been described, in which diphenylmethanols and their ether and ester derivatives are used as starting materials. Reductions are performed in ether under reflux and an argon atmosphere, and the addition of extra water is beneficial to this reduction. A series of alkanes are able to be prepared with good to excellent yields. A deuterated experiment exhibits that the reductive hydrogen is generated from ether. The mechanism is discussed in detail to explain the observed reactivity.

Superacid BF3-H2O promoted benzylation of arenes with benzyl alcohols and acetates initiated by trace water

A convenient procedure employing simple starting materials benzyl alcohols and acetates as the benzyl donors to assemble a series of diarylalkanes through benzylation of arenes using in situ prepared superacid BF3-H 2O as an efficient promoter has been developed. The beneficial role of water in the reaction has been clarified with combination of control experiments and 11B NMR analysis. This reaction is a self-promoted model, which is triggered by the trace of water and continuously promoted by self released by-product water (or carboxylic acid). A wide range of substrates are investigated and the moderate to excellent yields and the good regioselectivities for secondary benzyl alcohols as well as arenes bearing electron-withdrawing groups have been achieved. As a result, moisture in the reaction system has been utilized as an efficient initiator in all benzylation cases.