7520-97-0

Basic information

• Product Name: 4-methyl-2-phenyl-5-(2-phenylthiazol-4-yl)thiazole
• Synonyms: 4-methyl-2-phenyl-5-(2-phenylthiazol-4-yl)thiazole
• CAS NO: 7520-97-0
• Molecular Weight: 334.466
• Mol File: 7520-97-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-methyl-2-phenyl-5-(2-phenylthiazol-4-yl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-phenyl-5-(2-phenylthiazol-4-yl)thiazole(7520-97-0)
• EPA Substance Registry System: 4-methyl-2-phenyl-5-(2-phenylthiazol-4-yl)thiazole(7520-97-0)

Safety Data

• Hazardous Substances Data: 7520-97-0(Hazardous Substances Data)

Upstream product

• 123-54-6 acetylacetone 
• 3043-28-5 3-bromopentane-2,4-dione 
• 7520-94-7 5-acetyl-4-methyl-2-phenylthiazole 
• 7520-95-8 2-bromo-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-1-ethanone 
• 2227-79-4 benzenecarbothioamide 

Relevant articles and documents

Synthesis and biological screening of 2′-aryl/benzyl-2-aryl-4-methyl-4′,5-bithiazolyls as possible anti-tubercular and antimicrobial agents

A series of 2′-aryl/benzyl-2-aryl-4-methyl-4′,5-bithiazolyl derivatives, 25-64 were synthesized and evaluated for inhibitory activity against Mycobacterium smegmatis MC2 155 strain and antimicrobial activities against four pathogenic bacteria Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Proteus vulgaris. Among them, compounds 40, 49, 50, and 54 exhibited moderate to good inhibition on the growth of the bacteria Mycobacterium smegmatis at the concentration of 30 μM. Compounds 26, 40, 44, 54 and 56 exhibited moderate to good antibacterial activity. Compound 5-(2′-(4-fluorobenzyl)thiazol-4′-yl)-2-(4-fluorophenyl)-4-methyl-thiazole (54) exhibited both antitubercular as well as antimicrobial activity against all tested strains.