752212-23-0

Basic information

• Product Name: (1'S,2R)-tert-butyl 2-[1-acetoxy-1-(4-chlorophenyl)methyl]thiazolidine-3-carboxylate
• Synonyms: (1'S,2R)-tert-butyl 2-[1-acetoxy-1-(4-chlorophenyl)methyl]thiazolidine-3-carboxylate
• CAS NO: 752212-23-0
• Molecular Weight: 371.885
• Mol File: 752212-23-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1'S,2R)-tert-butyl 2-[1-acetoxy-1-(4-chlorophenyl)methyl]thiazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,2R)-tert-butyl 2-[1-acetoxy-1-(4-chlorophenyl)methyl]thiazolidine-3-carboxylate(752212-23-0)
• EPA Substance Registry System: (1'S,2R)-tert-butyl 2-[1-acetoxy-1-(4-chlorophenyl)methyl]thiazolidine-3-carboxylate(752212-23-0)

Safety Data

• Hazardous Substances Data: 752212-23-0(Hazardous Substances Data)

Upstream product

• 148312-55-4 tert-butyl thiazolidine-3-carboxylate 
• 104-88-1 4-chlorobenzaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 7477-64-7 (S)-1-(4-chlorophenyl)-1,2-ethanediol 

Relevant articles and documents

Highly enantioselective reaction of lithiated N-Boc-thiazolidine: A new chiral formyl anion equivalent

Reaction of lithiated N-Boc-thiazolidine 1 with various aldehydes in the presence of (-)-sparteine afforded the products with up to 93% ee. The reaction was confirmed to proceed through a dynamic thermodynamic resolution pathway. Each diastereomeric alcohol could be converted to the corresponding optically active 1,2-ethanediols.