752212-33-2Relevant articles and documents
Highly enantioselective reaction of lithiated N-Boc-thiazolidine: A new chiral formyl anion equivalent
Wang, Libo,Nakamura, Shuichi,Toru, Takeshi
, p. 2168 - 2169 (2007/10/03)
Reaction of lithiated N-Boc-thiazolidine 1 with various aldehydes in the presence of (-)-sparteine afforded the products with up to 93% ee. The reaction was confirmed to proceed through a dynamic thermodynamic resolution pathway. Each diastereomeric alcohol could be converted to the corresponding optically active 1,2-ethanediols.