752233-11-7Relevant articles and documents
(E)-3-Halo-2-styryl-4H-chromen-4-ones: Synthesis and transformation to novel pyrazoles
Ferreira, Joana P.A.,Silva, Vera L.M.,Elguero, José,Silva, Artur M.S.
, p. 9701 - 9709 (2013/10/22)
New methods for the synthesis of (E)-3-halo-2-styryl-4H-chromen-4-ones were established. The reaction of these compounds with hydrazine hydrate afforded new and unexpected 3(5)-aryl-5(3)-[2-(2-hydroxyphenyl)-2-hydrazonoethyl]-1H- pyrazoles, which upon aci
Synthesis and docking studies on styryl chromones exhibiting cytotoxicity in human breast cancer cell line
Bhatnagar, Seema,Sahi, Shakti,Kackar, Puneet,Kaushik, Swati,Dave, Manan K.,Shukla, Akshara,Goel, Ashita
scheme or table, p. 4945 - 4950 (2010/10/02)
The search for small molecules that preferentially target the functionally important surfaces of estrogen receptor and disrupt the transcriptional activity in the cell has emerged as a promising area towards rationale based drug design. Herein, we report substituted styryl chromones as a new class of compounds that exhibit selectivity for ERβ binding at the second binding site of HT and antiproliferative activity in human breast cancer cell line.
A novel and efficient route for the synthesis of hydroxylated 2,3-diarylxanthones
Santos, Clementina M. M.,Silva, Artur M. S.,Cavaleiro, José A. S.
, p. 3113 - 3116 (2008/09/19)
A novel, efficient and general route for the synthesis of hydroxylated 2,3-diarylxanthones is described. 3-Bromo-2-styryl-chromone, the key intermediate of this synthesis, is obtained by a Baker-Venkataraman rearrangement of the appropriate 2′-cinnamoylox
