7530-31-6

Basic information

• Product Name: 2-Propenamide, N-(4-aminophenyl)-
• CAS NO: 7530-31-6
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.191
• Mol File: 7530-31-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, N-(4-aminophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, N-(4-aminophenyl)-(7530-31-6)
• EPA Substance Registry System: 2-Propenamide, N-(4-aminophenyl)-(7530-31-6)

Safety Data

• Hazardous Substances Data: 7530-31-6(Hazardous Substances Data)

Usage

Description

2-Propenamide, N-(4-aminophenyl)-, also known as Acrylamide with a phenyl and amino group, is a chemical compound with the molecular formula C9H10N2O. It is an amide derivative characterized by the presence of a phenyl substituent and an amino group attached to the acrylamide backbone. This versatile chemical is known for its potential applications in various fields, including polymer and plastic production, pharmaceutical and agricultural chemical synthesis, dye and pigment manufacturing, and as a precursor in other chemical reactions. Its unique structure and properties have also attracted interest in the realms of organic chemistry and materials science research.

Uses

Used in Polymer and Plastics Industry:
2-Propenamide, N-(4-aminophenyl)is utilized as a monomer in the production of various polymers and plastics. Its ability to form co-polymers with other compounds contributes to the development of materials with tailored properties for specific applications.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Propenamide, N-(4-aminophenyl)serves as an intermediate in the synthesis of various drugs. Its reactivity and functional groups make it a valuable component in the creation of new medicinal compounds.
Used in Agricultural Chemicals:
2-Propenamide, N-(4-aminophenyl)is also employed in the synthesis of agricultural chemicals, where it can be used to develop new pesticides or other agrochemicals that improve crop yields and protect plants from diseases and pests.
Used in Dyes and Pigments Industry:
2-Propenamide, N-(4-aminophenyl)is used in the manufacturing of dyes and pigments, where its chemical structure allows for the production of a wide range of colors and shades for various applications, including textiles, paints, and inks.
Used in Organic Chemistry Research:
In the field of organic chemistry, 2-Propenamide, N-(4-aminophenyl)is studied for its potential as a precursor in various chemical reactions, providing insights into new synthetic pathways and the development of novel organic compounds.
Used in Materials Science Research:
2-Propenamide, N-(4-aminophenyl)-'s unique structure and properties make it a subject of interest in materials science, where it can be explored for its potential to contribute to the development of new materials with specific characteristics, such as improved conductivity, strength, or other desirable properties.

Upstream product

• 79-10-7 acrylic acid 
• 106-50-3 1,4-phenylenediamine 
• 71026-66-9 N-(tert-butoxycarbonyl)-1,4-phenylenediamine 
• 100-01-6 4-nitro-aniline 
• 7766-38-3 N-(4-nitrophenyl) acrylamide 
• 100-25-4 para-dinitrobenzene 
• 7439-89-6 iron 
• 814-68-6 acryloyl chloride 

Downstream Products

• 473430-67-0 N-{4-[4-(3,4,5-trimethoxy-phenylamino)-[1,3,5]triazin-2-ylamino]-phenyl}-acrylamide 
• 1374640-70-6 (N-(3-(2-(4-(4-acetylpiperazin-1-yl)-2-methoxyphenylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)phenyl)acrylamide) 
• 1357381-90-8 pyrrolidine-1-carboxylic acid (4-acryloylaminophenyl)-amide 

Relevant articles and documents

Discriminating detection of multiple analytes (F- and CN-) by a single probe through colorimetric and fluorescent dual channels

Abstract Two novel Schiff base type receptors containing phenol hydroxyl group (1) or methoxy group (2) were designed and synthesized. The receptor 1 with phenol hydroxyl group exhibited different colorimetric and fluorimetric responses to fluoride and cy

Design, synthesis and structure-activity relationship of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure as multi-target inhibitors against receptor tyrosine kinase

Inspired by that the multi-target inhibitors against receptor tyrosine kinases (RTKs) have significantly improved the effect of clinical treatment for cancer, and based on the chemical structure of Linifanib (ABT-869, Abbott), two series of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure were designed and synthesized as multi-target inhibitors against RTKs. The preliminary biological evaluation showed that several compounds exhibited comparable potency with Linifanib. Compound S21 was identified as the most potent inhibitor against Fms-like tyrosine kinase 3 (FLT-3), kinase insert domain containing receptor (KDR) and platelet-derived growth factor receptor β (PDGFR-β) with its IC50 values were 4 nM, 3 nM and 8 nM respectively, it also showed potent inhibitory activities against several cancer cells.

A polymerizable monomer preparation method and application of

The invention provides a preparation method and application of a polymerizable monomer. The method comprises the following steps of: (1) under the condition of an amidation reaction, enabling aromatic diamine with the structure as shown in the formula (I) to be in contact with acrylic so as to obtain an intermediate M with the structure as shown in the formula (II); and (2)under the condition of a condensation reaction, enabling the intermediate M to be in contact with binary fatty acid with the structure as shown in the formula (III) so as to obtain the polymerizable monomer as shown in the formula (IV), wherein n is an integer of 0-5, and m is an integer of 1-10. The purity and the yield of products obtained by the method are high, and the production cost is low. The polymerizable monomer provided by the invention is enabled to be co-polymerized to other monomers, so that an oil-driving polymer with high molecular, high apparent viscosity, excellent heat resistance and excellent salt resistance can be obtained. An oil displacement agent compounded by the polymer and a surfactant has higher stickiness, excellent heat resistance and excellent salt resistance.

PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS

The present invention provides kinase inhibitors with anti-proliferative activity comprising substituted pyrimidine derivatives and pharmaceutically-acceptable formulations thereof. In addition, the invention provides methods for making novel compounds and methods for using the compounds.