7537-08-8

Basic information

• Product Name: 2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE
• Synonyms: 2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE;3,4-Dimethoxy-2-fluorophenylacetonitrile
• CAS NO: 7537-08-8
• Molecular Formula: C₁₀H₁₀FNO₂
• Molecular Weight: 195.19
• Product Categories: Catechol Derivatives
• Mol File: 7537-08-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 48 °C
• Boiling Point: 122-135 °C(Press: 0.35-0.7 Torr)
• Appearance: /
• Density: 1.162±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE(7537-08-8)
• EPA Substance Registry System: 2-FLUORO-3,4-DIMETHOXYPHENYLACETONITRILE(7537-08-8)

Safety Data

• Hazardous Substances Data: 7537-08-8(Hazardous Substances Data)

Upstream product

• 1716-43-4 α-chloro-2-fluoro-3,4-dimethoxytoluene 
• 143-33-9 sodium cyanide 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 394-64-9 1-fluoro-2,3-dimethoxybenzene 
• 73943-41-6 2-fluoro-6-methoxyphenol 

Downstream Products

• 72912-24-4 2-fluoro-3,4-dimethoxyphenethyl amine 
• 78495-65-5 (2-fluoro-3,4-dimethoxyphenyl)acetic acid 
• 7537-12-4 2-(2-Fluoro-3,4-dimethoxy-phenyl)-3-oxo-butyronitrile 
• 103138-24-5 2-fluoro-3,4-dibenzyloxyphenylacetonitrile 
• 103138-28-9 2-(2'-fluoro-3',4'-dibenzyloxyphenyl)ethylamine 
• 72912-25-5 6-Fluoro-7,8-dimethoxy-1-(4-methoxy-phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine 
• 95413-95-9 N-<2-hydroxy-2-(4-methoxyphenyl)>-2-(3,4-dimethoxy-2-fluorophenyl)ethylamine 
• 104421-92-3 3-Allyl-6-fluoro-7,8-dimethoxy-1-(4-methoxy-phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine 
• 104421-99-0 N-<2-(4-methoxyphenyl)-2-hydroxyethyl>-2-(3,4-dimethoxy-2-fluorophenyl)acetamide 
• 104422-00-6 N-allyl-6-fluoro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrobromide 
• 103346-89-0 (2-fluoro-3,4-dimethoxyphenyl)acetyl chloride 
• 59043-74-2 <2-(2-fluoro-3,4-dimethoxyphenyl)ethyl>amine hydrobromide 
• 7537-16-8 1-(2-Fluoro-3,4-dimethoxy-phenyl)-propan-2-one 

Relevant articles and documents

Syntheses of Fluorinated 2-Benzylimidazolines

Perturbation of the electronic properties of the phenyl ring of 2-benzylimidazoline without appreciable steric modification can be achieved by fluorine substitution on the phenyl ring.The effects of such perturbation on biological activity can be evaluated.Syntheses of several fluorinated synthetic intermediates and 2-benzylimidazolines are described.Fluorine coupling of ortho benzylic protons and ortho methoxy protons were found to be 0-1.3 Hz.

Some nuclear-substituted derivatives of alpha-methyldopa.

-