7543-22-8

Basic information

• Product Name: 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone
• Synonyms: 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone;1-(2-PYRIDINYL)-2-(4-QUINOLINYL)ETHANONE
• CAS NO: 7543-22-8
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.27928
• Mol File: 7543-22-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone(7543-22-8)
• EPA Substance Registry System: 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone(7543-22-8)

Safety Data

• Hazardous Substances Data: 7543-22-8(Hazardous Substances Data)

Usage

General Description

2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone is a chemical compound with the molecular formula C16H12N2O. It is a synthetic organic compound that belongs to the class of heterocyclic compounds, containing both quinoline and pyridine moieties. 2-(quinolin-4-yl)-1-(pyridin-2-yl)-ethanone is commonly used in the field of medicinal chemistry and pharmaceutical research, where it is investigated for its potential biological activities and pharmacological properties. It is also employed as a building block or intermediate in the synthesis of various complex organic molecules, including pharmaceutical drugs and agrochemicals. Additionally, it may have applications in other industrial processes and scientific research endeavors.

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 2459-07-6 methyl pyridine-2-carboxylate 
• 2524-52-9 ethyl-2-picolinate 

Downstream Products

• 396129-53-6 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline 

Relevant articles and documents

Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-β type I receptor inhibitors

Optimization of the screening hit 1 led to the identification of novel 1,5-naphthyridine aminothiazole and pyrazole derivatives, which are potent and selective inhibitors of the transforming growth factor-β type I receptor, ALK5. Compounds 15 and 19, whic

Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain

We have expanded our previously reported series of pyrazole-based inhibitors of the TGF-β type I receptor kinase domain (TβR-I) to now include new 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole analogues. Limited examination of the SAR of this new series in both e