75431-14-0

Basic information

• Product Name: 2-(Hydroxymethyl)piperidine-N-carbamoyl chloride
• CAS NO: 75431-14-0
• Molecular Weight: 177.631
• Mol File: 75431-14-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(Hydroxymethyl)piperidine-N-carbamoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Hydroxymethyl)piperidine-N-carbamoyl chloride(75431-14-0)
• EPA Substance Registry System: 2-(Hydroxymethyl)piperidine-N-carbamoyl chloride(75431-14-0)

Safety Data

• Hazardous Substances Data: 75431-14-0(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 3433-37-2 piperidin-2-ylmethanol 

Relevant articles and documents

Anti-Bredt Molecules. 3. 3-Oxa-1-azabicyclononan-2-one and 6-Oxa-1-azabicyclooctan-7-one, Two Atom-Bridged Bicyclic Urethanes Possessing Bridgehead Nitrogen

The first atom-bridged bicyclic urethanes possessing bridgehead nitrogen have been synthesized and their properties examined briefly. 3-Oxa-1-azabicyclononan-2-one was synthesized from 3-(hydroxymethyl)-piperidine and phosgene by using two alternate reaction schemes. 6-Oxa-1-azabicyclooctan-7-one was synthesized similarly from 3-hydroxypiperidine.Both compounds were stable, white, crystalline solids with normal infrared spectra.They were rather stable to acids and bases, but phosphoric acid initiated ring-opening polymerization demonstrated strain in the system.A novel O -> N rearrangement of two aminochloroformates to hydroxy N-carbamoyl chlorides was demonstrated.