7544-97-0Relevant articles and documents
Alkylene diamines
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, (2008/06/13)
A cholinesterase inhibiting agent which contains an alkylene diamine of the formula STR1 wherein R 1 and R 2 each independently is a hydrogen atom or a hydrocarbon residue which may optionally be substituted, or R 1 and R 2 combinedly form, together with the adjacent nitrogen atom, a condensed heterocyclic group, R 3 is a hydrogen atom or a hydrocarbon residue or an acyl group which may optionally be substituted and R 4 is a hydrogen atom, or R 3 and R 4 combinedly form a group of the formula STR2 or --(CH 2) m+1 -- (m being 0, 1 or 2), A is --(CH 2) l -- (l being 0, 1 or 2) or --CH CH--, X is a substituent or substituents and n is an integer of 4 to 7, or a salt thereof, which are useful as cerebral function improving agents for the prevention or treatment of senile dementia, Alzheimer''s disease, Huntington''s chorea, hyperkinesia, mania and so forth.