75472-97-8Relevant articles and documents
Synthesis of Tetranuclear Iron-Sulphur Protein Analogues with Tetrathiol Ligands attached to Macrocycles which provide Intramolecular Hydrophobic Domains
Okuno, Hiroaki (Yohmei),Uoto, Kouichi,Tomohiro, Takenori,Youinou, Marie-Therese
, p. 3375 - 3381 (2007/10/02)
A new type of active-site analogues for 4Fe-4S iron-sulphur proteins is introduced, where the active site core is surrounded by an intramolecular hydrophobic domain formed by a 36-membered ring consisting of a methylene backbone.An efficient synthesis of the macrocyclic ligands 1,10,19,28-tetra(4-mercaptobenzoyl)-1,10,19,28-tetra-azacyclohexatriacontane and 1,10,19,28--1,10,19,28-tetra-azacyclohexatriacontane and 1,10,19,28-tetra-(3-mercapto-3-methylbutanoyl)-1,10,19,28-tetra-azacyclohexatriacontane is described.Their reaction with t)4>2- afforded novel clusters in good yields (70 - 90percent) as black powders with m.p. > 300 deg C.They dissolve in dimethylformamide, dimethyl sulphoxide, and propylene carbonate.Complex formation with Fe4S4 clusters was mainly demonstrated by u.v.-visible and n.m.r. studies and the properties of the new clusters are discussed.
