754920-30-4

Basic information

• Product Name: (4-(difluoromethyl)phenyl)methanamine
• CAS NO: 754920-30-4
• Molecular Weight: 157.163
• Mol File: 754920-30-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 218.3±35.0 °C(Predicted)
• Density: 1.144±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (4-(difluoromethyl)phenyl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(difluoromethyl)phenyl)methanamine(754920-30-4)
• EPA Substance Registry System: (4-(difluoromethyl)phenyl)methanamine(754920-30-4)

Safety Data

• Hazardous Substances Data: 754920-30-4(Hazardous Substances Data)

Usage

Description

(4-(difluoromethyl)phenyl)methanamine, also known as 4-(difluoromethyl)benzylamine, is a chemical compound with the formula C8H10F2N. It is a primary aliphatic amine that contains a difluoromethyl group attached to a phenyl ring. (4-(difluoromethyl)phenyl)methanamine is characterized by its unique structural and functional properties, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
(4-(difluoromethyl)phenyl)methanamine is used as a building block for the preparation of various pharmaceuticals. Its unique difluoromethyl group can be incorporated into drug candidates to enhance their pharmacological properties, such as potency, selectivity, and metabolic stability.
Used in Agrochemical Industry:
In the agrochemical industry, (4-(difluoromethyl)phenyl)methanamine serves as a key intermediate for the synthesis of agrochemicals. The difluoromethyl group can impart specific biological activities to these compounds, such as herbicidal, insecticidal, or fungicidal properties, making them more effective in agricultural applications.
Used in Organic Synthesis:
(4-(difluoromethyl)phenyl)methanamine is used as a reagent in organic synthesis to introduce the difluoromethyl substituent into organic molecules. This can lead to the development of new compounds with improved properties, such as increased lipophilicity, metabolic stability, or binding affinity.
Used in Medicinal Chemistry:
The difluoromethyl group in (4-(difluoromethyl)phenyl)methanamine is of interest in medicinal chemistry due to its unique properties. It can be used to modify the structure of drug candidates, potentially improving their pharmacokinetics, pharmacodynamics, and safety profiles.
Used in Material Science:
(4-(difluoromethyl)phenyl)methanamine has the potential to be utilized in the development of new functional materials due to its structural and functional properties. The difluoromethyl group can be incorporated into various materials to enhance their properties, such as thermal stability, chemical resistance, or electronic properties.

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 55805-10-2 4-cyano-1-difluoromethylbenzene