754977-12-3

Basic information

• Product Name: 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline
• Synonyms: 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline
• CAS NO: 754977-12-3
• Molecular Weight: 370.579
• Mol File: 754977-12-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline(754977-12-3)
• EPA Substance Registry System: 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline(754977-12-3)

Safety Data

• Hazardous Substances Data: 754977-12-3(Hazardous Substances Data)

Upstream product

• 327044-56-4 6-Hydroxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 120-15-0 6-methoxy-1,2,3,4-tetrahydroquinoline 
• 3373-00-0 6-hydroxy-1,2,3,4-tetrahydroquinoline 
• 5263-87-6 6-methoxy quinoline 
• 676254-99-2 6-(3-piperidin-1-yl-propoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 

Downstream Products

• 676255-02-0 1-cyclohexylmethyl-6-(3-piperidin-1-yl-propoxy)-1,2,3,4-tetrahydro-quinoline hydrochloride 

Relevant articles and documents

Synthesis and SAR of novel histamine H3 receptor antagonists

The synthesis and biological evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline, and tetrahydroazepine antagonists of the human and rat H3 receptors are described. The substitution around these rings as well as the nature of the substituent on nitrogen is explored. Several compounds with high affinity and selectivity for the human and rat H3 receptors are reported.