755024-79-4Relevant articles and documents
Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action
Pessoa-Mahana, Hernan,Gajardo, Gonzalo Recabarren,Araya-Maturana, Ramiro,Carcamo, Johann Kosche,Pessoa-Mahana, C. David
, p. 2513 - 2521 (2007/10/03)
We report here the synthesis of substituted 4-chloro-N-[3-oxo-3-(4-aryl-1- piperazinyl)-propyl] benzamides (5-9), as potential new antidepressants, incorporating in a single molecule structural moieties related to a dual pharmacological profile: MAO-A inh