755027-18-0

Basic information

• Product Name: 2-BROMO-5-IODOANISOLE
• Synonyms: 2-BROMO-5-IODOANISOLE;Benzene, 1-broMo-4-iodo-2-Methoxy-;1-Bromo-4-iodo-2-methoxybenzene, 2-Bromo-5-iodophenyl methyl ether;2-BroMo-5-iodophenyl Methyl ether
• CAS NO: 755027-18-0
• Molecular Formula: C₇H₆BrIO
• Molecular Weight: 312.93
• Product Categories: Aromatic Halides (substituted);Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Iodine Compounds
• Mol File: 755027-18-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 293.7 °C at 760 mmHg
• Flash Point: 131.4 °C
• Appearance: /
• Density: 2.062
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: 2-BROMO-5-IODOANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-IODOANISOLE(755027-18-0)
• EPA Substance Registry System: 2-BROMO-5-IODOANISOLE(755027-18-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 755027-18-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-iodoanisole is a chemical compound with the molecular formula C7H6BrIO. It is a derivative of anisole, a methoxybenzene, with bromine and iodine substituents. 2-Bromo-5-iodoanisole is mainly used as a reagent in organic synthesis and as an intermediate for the production of various pharmaceuticals, agrochemicals, and other fine chemicals. 2-Bromo-5-iodoanisole is also used in the preparation of advanced materials and in research and development in the field of organic chemistry. Its specific properties and applications make it a useful and versatile chemical in various industries.

Upstream product

• 932372-99-1 2-bromo-5-iodophenol 
• 77-78-1 dimethyl sulfate 
• 19056-40-7 4-bromo-3-methoxyaniline 
• 89942-34-7 2-methoxy-4-iodobenzoic acid 

Downstream Products

• 43192-34-3 4-bromo-3-methoxybenzaldehyde 
• 932372-99-1 2-bromo-5-iodophenol 
• 924271-33-0 (2E)-3-(4-bromo-3-methoxyphenyl)acrylic acid 
• 1025369-59-8 2-amino-4'-bromo-3'-methoxybiphenyl-4-carbonitrile 
• 1160360-15-5 C₁₈H₂₇BrO₂Si 
• 1103535-39-2 3-(4-bromo-3-methoxyphenyl)thiophene-2-carboxylic acid 
• 1103535-36-9 ethyl 2-(4-bromo-3-methoxyphenyl)cyclohex-1-ene-1-carboxylate 
• 1313809-06-1 C₃₈H₆₆OSi₂ 
• 1313809-07-2 C₃₅H₅₈OSi 
• 1450922-43-6 4-(3'-fluoro-3-methoxy-[1,1'-biphenyl]-4-yl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide 
• 1353855-71-6 C₁₀H₁₁BrO 
• 1443377-33-0 2-(4-cyclopropyl-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1467061-02-4 methyl 6-chloro-5-[4-(1-hydroxycyclobutyl)-3-methoxyphenyl]-1H-indole-3-carboxylate 
• 1467064-51-2 6-chloro-5-[4-(1-hydroxycyclobutyl)-3-methoxyphenyl]-1H-indole-3-carboxylic acid 

Relevant articles and documents

Using Nature's polyenes as templates: studies of synthetic xanthomonadin analogues and realising their potential as antioxidants

Two truncated analogues of the polyenyl photoprotective xanthomonadin pigments have been synthesised utilising an iterative Heck-Mizoroki (HM)/iododeboronation cross coupling approach and investigated as models of the natural product photoprotective agent

Transition-metal-free decarboxylative bromination of aromatic carboxylic acids

Methods for the conversion of aliphatic acids to alkyl halides have progressed significantly over the past century, however, the analogous decarboxylative bromination of aromatic acids has remained a longstanding challenge. The development of efficient methods for the synthesis of aryl bromides is of great importance as they are versatile reagents in synthesis and are present in many functional molecules. Herein we report a transition metal-free decarboxylative bromination of aromatic acids. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggests that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials.

Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet

We have developed a family of unnatural base pairs (UBPs), exemplified by the pair formed between dNaM and dTPT3, for which pairing is mediated not by complementary hydrogen bonding but by hydrophobic and packing forces. These UBPs enabled the creation of