75510-81-5

Basic information

• Product Name: (E)-3-(3-Methoxy-phenylsulfanyl)-but-2-enoic acid
• Synonyms: (E)-3-(3-Methoxy-phenylsulfanyl)-but-2-enoic acid
• CAS NO: 75510-81-5
• Molecular Weight: 224.28
• Mol File: 75510-81-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-(3-Methoxy-phenylsulfanyl)-but-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(3-Methoxy-phenylsulfanyl)-but-2-enoic acid(75510-81-5)
• EPA Substance Registry System: (E)-3-(3-Methoxy-phenylsulfanyl)-but-2-enoic acid(75510-81-5)

Safety Data

• Hazardous Substances Data: 75510-81-5(Hazardous Substances Data)

Upstream product

• 6214-28-4 (E)-3-chloro-2-butenoic acid 
• 15570-12-4 3-methoxybenzenethiol 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 40053-33-6 7-methoxy-4-methylbenzo[e]thiin-2-one 

Relevant articles and documents

Synthesis of 2H-1-Benzothiopyran-2-ones (Thiocoumarins) and Related Compounds from Benzenethiols and Diketene

The products formed by the reaction of benzenethiols with diketene in the presence of H2SO4 are (E)-β-(arylthio)crotonic acids (2) and/or isomeric (Z)-β-(arylthio)crotonic acids and not, as has been reported, S-phenyl-3-oxobutanethioates (1).Compounds 1a-k, as the precursor of thiocoumarins, were prepared from benzenethiols and diketene in the presence of triethylamine.The reaction of 1 with various condensing agents has been examined to prepare 2H-1-benzothiopyran-2-ones (thiocoumarins).It is found that 4-methyl(thiocoumarins) were conveniently prepared by thereaction of 1 with anhydrous aluminium chloride in yields of 16-48percent.When 1 was treated with PPA, isomeric 2-methyl(thiochromones) were preferentially obtained in yields of 5-66percent, and compound 2 was isolated as an intermediate.The spectral characteristics of 4-methyl(thiocoumarins) have also been described.