75523-42-1

Basic information

• Product Name: 4-(CHLOROMETHYL)-2-METHYLPYRIDINE
• Synonyms: 4-(CHLOROMETHYL)-2-METHYLPYRIDINE;pyridine, 4-(chloroMethyl)-2-Methyl-;4-(Chloromethyl)-2-picoline;2-Methyl-4-(chloromethyl)pyridine;2-methyl-pyridin-4-ylmethyl chloride;4-Chloromethyl-2-methyl-pyridine.HCL
• CAS NO: 75523-42-1
• Molecular Formula: C₇H₈ClN
• Molecular Weight: 141.6
• EINECS: 604-604-1
• Product Categories: Aromatics, Heterocycles, Miscellaneous Reagents
• Mol File: 75523-42-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 218℃
• Flash Point: 106℃
• Appearance: /
• Density: 1.118
• Vapor Pressure: 0.194mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: 4-(CHLOROMETHYL)-2-METHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(CHLOROMETHYL)-2-METHYLPYRIDINE(75523-42-1)
• EPA Substance Registry System: 4-(CHLOROMETHYL)-2-METHYLPYRIDINE(75523-42-1)

Safety Data

• Hazardous Substances Data: 75523-42-1(Hazardous Substances Data)

Usage

Uses

4-Chloromethyl-2-methylpyridine is used in the preparation of HIV-1 protease inhibitors.

InChI:InChI=1/C7H8ClN/c1-6-4-7(5-8)2-3-9-6/h2-4H,5H2,1H3

Upstream product

• 105250-16-6 (2-methylpyridin-4-yl)methanol 
• 1122-45-8 2,4-dimethylpyridine N-oxide 
• 74405-07-5 4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine 

Downstream Products

• 130138-46-4 2-(2-methylpyridin-4-yl)acetonitrile 

Relevant articles and documents

NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS

The invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis.

PYRIDYLISOXAZOLE DERIVATIVE

This invention offers isoxazole derivatives represented by the following formula (I) in which R1 and R2 each stands for hydrogen, lower alkyl, amino and the like; R3 stands for substituted or unsubstituted aryl or hetero a

Heterocycles substituted pyridine derivatives and antifungal agent containing thereof

An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound represented by the following formula (I), or a salt thereof: wherein R1 represents a hydrogen atom, a halogen atom, an amino group, a C1-6 alkyl group, a C1-6 alkoxy group or a C1-6 alkoxy C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group or a di C1-6 alkylamino group; one of X and Y is a nitrogen atom while the other is a nitrogen atom or an oxygen atom; ring A represents a 5- or 6-member heteroaryl ring or a benzene ring which may have a halogen atom, or 1 or 2 C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, a sulfur atom, —CH2O—, —OCH2—, —NH—, —CH2NH—, —NHCH2—, —CH2S—, or —SCH2—; R3 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C3-8 cycloalkyl group, a C6-10 aryl group, a 5- or 6-member heteroaryl group, or 5- or 6-member non-aromatic heterocyclic group which may have 1 or 2 substituents; and R4 represents a hydrogen atom or a halogen atom.