75527-87-6Relevant articles and documents
METHODS OF SYNTHESIS AND TECHNOLOGY OF MANUFACTURE OF DRUGS. CATALYTIC REDUCTION OF 6,6-DIBROMOPENICILLANIC ACID 1,1-DIOXIDE
Lelyak, G. F.,Povalyaeva, E. A.,Filatova, A. A.,Mezentsev, A. S.,Mikhalev, A. V.
, p. 847 - 849 (2007/10/02)
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Intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 is H or HO; Y and Z are each Cl, Br or I, or Y is H and Z is Cl, Br or I; Q is N3 or NHCO2 CH2 C6 H4 R4 where R4 is H, Cl, Br,
Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
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, (2008/06/13)
Process for preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide of the formula STR1 where X is Cl, Br, I, certain alkylsulfonyloxy or arylsulfonyloxy groups, useful as intermediates in production of antibiotics having beta-lactamase activity, which comprises hydrogenolysis of an ester of the formula STR2 where n is zero, 1 or 2; Y and Z are each Cl, Br or I, or Y is H and Z is Cl, Br, I, C N-- or SCN--, or Y is arylselenyl and Z is Cl or Br; and when n is zero or 1, oxidation of the hydrogenolysis product; a process for preparing compounds of formula (VI, n=2) by oxidation of the corresponding compound (VI) wherein n is zero or 1, and certain novel intermediates useful in the above processes.