75530-05-1Relevant articles and documents
Stereochemistry of the 2-Hydroxy-1,2,3,4-tetrahydropyridine Intermediate of Hantzsch Cyclization
Ogawa, Toshihisa,Matsumoto, Keita,Yoshimura, Misa,Hatayama, Katsuo,Kitamura, Kunihiro,Kita, Yasuyuki
, p. 1967 - 1970 (2007/10/02)
Hantzsch cyclization of cyanoethyl 3-aminocrotonate and (E,Z)-4-dialkoxymethyl-2-benzylidene-acetoacetates (5a,b) afforded 3,4-trans-2-hydroxy-1,2,3,4-tetrahydropyridines (7a,b) in high stereoselectivity.