7554-79-2

Basic information

• Product Name: (2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID
• Synonyms: (2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID;2-[(2,4-DICHLOROBENZOYL)AMINO]ACETIC ACID;AURORA 15900;OTAVA-BB BB7012350676;N-(2,4-Dichlorobenzoyl)glycine;(2,4-dichlorobenzoyl)glycine
• CAS NO: 7554-79-2
• Molecular Formula: C₉H₇Cl₂NO₃
• Molecular Weight: 248.06
• Mol File: 7554-79-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 156-160°C
• Boiling Point: 438.1°C at 760 mmHg
• Flash Point: 218.7°C
• Appearance: /
• Density: 1.505g/cm³
• Vapor Pressure: 1.9E-08mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: (2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID(7554-79-2)
• EPA Substance Registry System: (2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID(7554-79-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 7554-79-2(Hazardous Substances Data)

Usage

General Description

(2,4-DICHLORO-BENZOYLAMINO)-ACETIC ACID, also known as dicamba, is a synthetic organic compound used as a broadleaf herbicide. It works by disrupting the growth of unwanted plants without harming grasses and grains. Dicamba is commonly used in agricultural settings, particularly for controlling weeds in crops such as soybeans, cotton, and corn. It is also used in residential and commercial settings for weed control. Dicamba has been the subject of controversy due to its potential to drift and cause damage to neighboring crops, leading to legal battles and restrictions on its use in certain regions. However, it remains an important tool for weed management in agriculture.

InChI:InChI=1/C9H7Cl2NO3/c10-5-1-2-6(7(11)3-5)9(15)12-4-8(13)14/h1-3H,4H2,(H,12,15)(H,13,14)

Upstream product

• 89-75-8 2,4-dichlorobenzoyl chloride 
• 56-40-6 glycine 
• 50-84-0 2,4 dichlorobenzoic acid 

Downstream Products

• 16352-88-8 2-(2,4-Dichlor-phenyl)-4-furfuryliden-oxazolinon-5 
• 16352-86-6 2-(2,4-Dichlor-phenyl)-4-piperonyliden-oxazolinon-(5) 
• 16352-82-2 4-(2-chloro-benzylidene)-2-(2,4-dichloro-phenyl)-4H-oxazol-5-one 
• 16352-81-1 4-benzylidene-2-(2,4-dichloro-phenyl)-4H-oxazol-5-one 
• 16352-84-4 2-(2,4-dichloro-phenyl)-4-(3,4-dimethoxy-benzylidene)-4H-oxazol-5-one 
• 16352-87-7 2-(2,4-dichloro-phenyl)-4-(3-phenyl-allylidene)-4H-oxazol-5-one 
• 16352-85-5 2-(2,4-dichloro-phenyl)-4-(4-dimethylamino-benzylidene)-4H-oxazol-5-one 
• 132311-61-6 2,4-Dichloro-N-(p-tolylcarbamoyl-methyl)-benzamide 
• 132311-60-5 2,4-Dichloro-N-phenylcarbamoylmethyl-benzamide 
• 132311-62-7 2,4-Dichloro-N-[(4-phenoxy-phenylcarbamoyl)-methyl]-benzamide 
• 896742-21-5 (4Z)-2-(2,4-dichlorophenyl)-4-(2-furylmethylene)oxazol-5-one 

Relevant articles and documents

Synthesis and evaluation of new phenyl acrylamide derivatives as potent non-nucleoside anti-HBV agents

As a continuation of our previous work, a series of new phenyl acrylamide derivatives (4Aa-g, 4Ba-t, 5 and 6a-c) were designed and synthesized as non-nucleoside anti-HBV agents. Among them, compound 4Bs could potently inhibit HBV DNA replication in wild-type and lamivudine (3TC)/entecavir resistant HBV mutant strains with IC50 values of 0.19 and 0.18 μM, respectively. Notably, the selective index value of 4Bs was above 526, indicating the favorable safety profile. Interestingly, unlike nucleoside analogue 3TC, 4Bs could significantly inhibit 3.5 kb pgRNA expression. Molecular docking study revealed that 4Bs could fit well into the dimer-dimer interface of HBV core protein by hydrophobic, π–π and H-bond interactions. Considering the potent anti-HBV activity, low toxicity and diverse anti-HBV mechanism from that of nucleoside anti-HBV agent 3TC, compound 4Bs might be a promising lead to develop novel non-nucleoside anti-HBV therapeutic agents, and warranted further investigation.

Synthesis and insect growth regulating activity of structurally modified benzoylphenylureas

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