75613-95-5Relevant articles and documents
Synthesis and biological screening of new cyano-substituted pyrrole fused (Iso)quinoline derivatives
Al-Matarneh, Maria Cristina,Am?randi, Roxana-Maria,Danac, Ramona,Mangalagiu, Ionel I.
, (2021/05/29)
Several new cyano-substituted derivatives with pyrrolo[1,2-a]quinoline and pyrrolo[2,1a]isoquinoline scaffolds were synthesized by the [3 + 2] cycloaddition of (iso)quinolinium ylides to fumaronitrile. The cycloimmonium ylides reacted in situ as 1,3-dipol
Synthesis and biological evaluation of some new indolizine derivatives as antitumoral agents
Lucescu, Liliana,B?cu, Elena,Belei, Dalila,Dubois, Jo?lle,Ghinet, Alina
, p. 479 - 488 (2016/07/19)
A new series of indolizine derivatives were synthesized and screened for the antiproliferative potential against NCI 60 tumor cell line panel. The results of the study revealed a selective and good antitumor growth inhibitory activity against SNB-75 CNS c
Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events
Lucescu, Liliana,Ghinet, Alina,Belei, Dalila,Rigo, Beno?t,Dubois, Jo?lle,B?cu, Elena
supporting information, p. 3975 - 3979 (2015/08/24)
Abstract A new family of 3-aroylindolizines bearing a dimethoxytriazine unit in their position 1 was designed, synthesized and evaluated for their ability to inhibit tubulin polymerization and cellular growth in vitro. Compound 39 was the best candidate i
