75637-65-9

Basic information

• Product Name: 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline
• Synonyms: 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline
• CAS NO: 75637-65-9
• Molecular Weight: 319.386
• Mol File: 75637-65-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline(75637-65-9)
• EPA Substance Registry System: 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline(75637-65-9)

Safety Data

• Hazardous Substances Data: 75637-65-9(Hazardous Substances Data)

Upstream product

• 609-72-3 N,N-dimethyl-o-toluidine 
• 1079-66-9 chloro-diphenylphosphine 
• 4376-01-6 sodium diphenylphosphide 

Downstream Products

• 913849-07-7 trans-[RhCl(CO)((C₆H₅)2PCH₂(C₆H₄)N(CH₃)2)2] 
• 913849-04-4 [RhCl(1,5-cyclooctadiene)((C₆H₅)2PCH₂(C₆H₄)N(CH₃)2)] 

Relevant articles and documents

Oxidation reactions, coordination chemistry and antibacterial activities with ligand 2-{(diphenylphosphino)methyl}-N,N-dimethylaniline

N,N-dimethyl-o-toluidine was treated with n-butyllithium-tmeda in diethylether/hexane solution to give (2-(dimethylamino)benzyl)lithium which reacts with chlorodiphenylphosphine to form the corresponding hemilabile N,P-ligand 2-PPh2CH2-1-NMe2C6H4 (1). Oxidation of 1 with elemental sulfur or gray selenium gave the corresponding sulfide and selenide 2-(E)PPh2CH2-1-NMe2C6H4 (E = S (2), Se (3)), respectively. The reaction of 1 with M(CO)6 (M = Mo, W) afforded cis-[Mo(CO)4{2-PPh2CH2-1-NMe2C6H4 }2](4) and trans-[W(CO)4{2-PPh2CH2-1-NMe2C6H4 }2](5), respectively. The treatment of 1 with copper(I) iodide in 1:1 mol ratio produced [CuI{2-PPh2CH2-1-NMe2C6H4 }]2 (6). The complexes 4–6 have been screened for antibacterial activity and the results were compared with the activity of the free ligand 1 against four bacterial strains. Complexes 4 and 6 had the highest antibacterial activity and can be considered as promising antimicrobial agents. Compounds 1–6 were characterized by multinuclear NMR spectroscopy (1H, 13C, 31P, 77Se NMR), IR and elemental analysis. Crystal structure determinations of 1, 2, 4, and 6 were carried out.

ORGANOARSENEVERBINDUNGEN: 39 SUBSTITUERTE BENZYLPHOSPHINE UND -ARSINE ALS LEICHT ZUGAENGLICHE BIDENTATE LIGANDEN

2-Hydroxybenzylamines or 2- and 4-aminobenzylamines react with diphenylphosphine at higher temperature to give hydroxy-substituted and aminosubstituted benzylphosphines, respectively.This reaction fails in the case of alkoxy or dialkylaminobenzyl amines.T