756521-06-9Relevant articles and documents
1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1
Rahman, Shahzad S.,Coulton, Steven,Herdon, Hugh J.,Joiner, Graham F.,Jin, Jian,Porter, Roderick A.
, p. 1741 - 1745 (2008/02/11)
High throughput screening led to the discovery of a novel series of 1,3-diaminopropan-2-ol sulfonamides as selective GlyT-1 inhibitors. Structure-activity relationships of this novel series and optimisation of the initial hit that led to the identificatio
AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS
-
Page 99, (2010/02/08)
Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.
