75657-73-7

Basic information

• Product Name: N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl ester
• CAS NO: 75657-73-7
• Molecular Weight: 363.411
• Mol File: 75657-73-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl ester(75657-73-7)
• EPA Substance Registry System: N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl ester(75657-73-7)

Safety Data

• Hazardous Substances Data: 75657-73-7(Hazardous Substances Data)

Upstream product

• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 
• 63734-73-6 ethyl (2S,3S)-2,3-epoxysuccinate 
• 1738-69-8 L-Leucine benzyl ester 
• 3291-46-1 (2S,3S)-diethyl oxirane-2,3-dicarboxylate 

Downstream Products

• 88321-09-9 aloxistatin 

Relevant articles and documents

A new synthesis of peptidyl epoxysuccinates for probing cysteine protease-inhibitor P3/S3 binding interactions

A new synthesis of peptidyl epoxysuccinates has been developed involving the N-acylation of amino acid benzyl esters (12) with the tartrate ester derived epoxy acid 13 followed by deprotection of the benzyl esters and acylation with amines 21-28. This syn

E-64 analogs as inhibitors of cathepsin L and cathepsin S: Importance of the S2-P2 interactions for potency and selectivity

A number of epoxysuccinyl amino acid benzyl esters (HO-Eps-AA-OBzl, 1) in which the amino acid (AA) had been systematically varied were tested as inhibitors of cathepsins L and S. These E-64 analogs were designed to investigate whether selectivity for cat