75667-84-4 Usage
Description
4-Acetyl-1,1-dimethylpiperazinium Iodide, also known as AChR agonist, is a structural analog of acetylcholine. It possesses the ability to interact with acetylcholine receptors, making it a potential candidate for various applications in the pharmaceutical and medical fields.
Uses
Used in Pharmaceutical Industry:
4-Acetyl-1,1-dimethylpiperazinium Iodide is used as a pharmacological agent for its agonistic effects on acetylcholine receptors. It can be utilized in the development of drugs targeting neurological disorders and conditions related to the cholinergic system.
Used in Research and Development:
In the field of research, 4-Acetyl-1,1-dimethylpiperazinium Iodide serves as a valuable tool for studying the function and mechanisms of acetylcholine receptors. It can be employed in experiments to investigate the effects of AChR agonists on receptor activity, signal transduction pathways, and related cellular processes.
Used in Neurological Applications:
4-Acetyl-1,1-dimethylpiperazinium Iodide is used as a therapeutic agent for neurological conditions that involve the cholinergic system, such as Alzheimer's disease, myasthenia gravis, and other disorders characterized by impaired acetylcholine signaling. Its agonistic properties can help in modulating the cholinergic system and potentially improve the symptoms of these conditions.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of 4-Acetyl-1,1-dimethylpiperazinium Iodide, various drug delivery systems can be developed. These systems may include encapsulation in nanoparticles, liposomes, or other carriers, aiming to improve the delivery of the compound to target tissues and cells, as well as to reduce potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 75667-84-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,6 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75667-84:
(7*7)+(6*5)+(5*6)+(4*6)+(3*7)+(2*8)+(1*4)=174
174 % 10 = 4
So 75667-84-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H17N2O.HI/c1-8(11)9-4-6-10(2,3)7-5-9;/h4-7H2,1-3H3;1H/q+1;/p-1
75667-84-4Relevant articles and documents
Polyethylene glycol-based homologated ligands for nicotinic acetylcholine receptors
Scates, Bradley A.,Lashbrook, Bethany L.,Chastain, Benjamin C.,Tominaga, Kaoru,Elliott, Brandon T.,Theising, Nicholas J.,Baker, Thomas A.,Fitch, Richard W.
, p. 10295 - 10300 (2008)
A homologous series of polyethylene glycol (PEG) monomethyl ethers were conjugated with three ligand series for nicotinic acetylcholine receptors. Conjugates of acetylaminocholine, the cyclic analog 1-acetyl-4,4-dimethylpiperazinium, and pyridyl ether A-84543 were prepared. Each series was found to retain significant affinity at nicotinic receptors in rat cerebral cortex with tethers of up to six PEG units. Such compounds are hydrophilic ligands which may serve as models for fluorescent/affinity probes and multivalent ligands for nAChR.
