75762-58-2 Usage
Description
3-Bromo-3'-fluorobenzophenone, with the chemical formula C13H8BrFO, is a white crystal solid that possesses a molecular weight of 271.1 g/mol. This chemical compound is recognized for its versatile reactivity and is frequently utilized as a building block in organic synthesis and pharmaceutical research. Its unique chemical structure also grants it potential applications in the development of new materials and polymers.
Uses
Used in Pharmaceutical Research:
3-Bromo-3'-fluorobenzophenone is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure and reactivity make it a valuable component in medicinal chemistry.
Used in Agrochemical Production:
3-BROMO-3'-FLUOROBENZOPHENONE is also employed as a building block in the creation of agrochemicals, playing a role in the development of pesticides and other agricultural products designed to protect crops and enhance yields.
Used in Dye Manufacturing:
3-Bromo-3'-fluorobenzophenone is utilized in the production of dyes, where its chemical properties contribute to the color and stability of the final products.
Used in Material and Polymer Development:
Due to its distinctive chemical structure, 3-bromo-3'-fluorobenzophenone has potential applications in the research and development of innovative materials and polymers, which could have a wide range of uses across various industries.
Safety Precautions:
It is crucial to handle 3-bromo-3'-fluorobenzophenone with care, as it is considered harmful if inhaled and may cause skin and eye irritation upon contact. Proper safety measures should be taken to minimize risks during its use and manipulation.
Check Digit Verification of cas no
The CAS Registry Mumber 75762-58-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75762-58:
(7*7)+(6*5)+(5*7)+(4*6)+(3*2)+(2*5)+(1*8)=162
162 % 10 = 2
So 75762-58-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H8BrFO/c14-11-5-1-3-9(7-11)13(16)10-4-2-6-12(15)8-10/h1-8H
75762-58-2Relevant articles and documents
Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors
Kishore Kumar,Chavarria, Gustavo E.,Charlton-Sevcik, Amanda K.,Arispe, Wara M.,MacDonough, Matthew T.,Strecker, Tracy E.,Chen, Shen-En,Siim, Bronwyn G.,Chaplin, David J.,Trawick, Mary Lynn,Pinney, Kevin G.
supporting information; experimental part, p. 1415 - 1419 (2010/07/06)
A small library of 36 functionalized benzophenone thiosemicarbazone analogs has been prepared by chemical synthesis and evaluated for their ability to inhibit the cysteine proteases cathepsin L and cathepsin B. Inhibitors of cathepsins L and B have the potential to limit or arrest cancer metastasis. The six most active inhibitors of cathepsin L (IC50 50 > 10,000 nM). The most active analog in the series, 3-bromophenyl-2′-fluorophenyl thiosemicarbazone 1, also efficiently inhibits cell invasion of the DU-145 human prostate cancer cell line.
