7578-24-7

Basic information

• Product Name: lacto-N-tetraose
• CAS NO: 7578-24-7
• Molecular Weight: 707.637
• Mol File: 7578-24-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: lacto-N-tetraose(CAS DataBase Reference)
• NIST Chemistry Reference: lacto-N-tetraose(7578-24-7)
• EPA Substance Registry System: lacto-N-tetraose(7578-24-7)

Safety Data

• Hazardous Substances Data: 7578-24-7(Hazardous Substances Data)

Upstream product

• 875712-82-6 benzyl O-β-D-galactopyranosyl-(1->3)-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->3)-O-β-D-galactopyranosyl-(1->4)-O-β-D-glucopyranoside 
• 875712-80-4 O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate 
• 50611-42-2 β-D-galactopyranosyl-(1->4)-1-thio-β-D-glucopyranoside 
• 15839-70-0 guanosine-5'-diphospho-β-L-fucose 
• 123073-98-3 NeuAc(α2-3)Gal(β1-3)GlcNAc(β1-3)Gal(β1-4)Glc 
• 71512-64-6 (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-(2-acetamido-2-deoxy-4,6-di-O-acetyl-β-D-glucopyranosyl)-(1->3)-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1->4)-1,2,3-6-tetra-O-acetyl-α,β-D-glucopyranose 

Downstream Products

• 314075-31-5 β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->3)-β-D-galactopyranosyl-(1->4)-D-[N-acetyl-N-(4-benzyloxycarbonylaminophenyl)-1-amino-1-deoxy]-glucitol 
• 64003-53-8 (5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2-3)-β-D-galactopyranosyl-(1-3)-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1-3)-β-D-galactopyranosyl-(1-4)-α,β-D-glucopyranose 

Relevant articles and documents

Chemical Synthesis of Human Milk Oligosaccharides: Lacto- N-hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc

The first synthesis of lacto-N-hexaose (LNH) has been completed using a convergent strategy. The donor-acceptor protecting-leaving group combinations were found to be of paramount significance for achieving successful glycosylations and minimizing side re

SYNTHESIS OF HMO CORE STRUCTURES

The invention relates to a method for making precursors of HMO core structures comprising a step of reacting an N-acetyllactosamine or lacto-N-biose derivative donor with a lactose or N-acetyllactosamine derivative acceptor, wherein the donor is an oxazol

Chemo-enzymatic supported synthesis of the 3-sulfated Lewisa pentasaccharide on a multimeric polyethylene glycol

The 3-sulfated Lewisa pentasaccharide was synthesized on multimeric-based polyethylene glycol support. Coupling of O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-(1→3)-4,6-di-O -acetyl-2-deoxy-2-phthalimido-β-d-glucopyranosyl trichloroacetimidate with (2,6-di-O-acetyl-β-d-galactopyranosyl)-(1→4)-(2,3,6-tri-O-acet yl-β-d-glucopyranoside) bound onto the polymer afforded lacto-N-tetraose, which was then regioselectively sulfated at the 3-OH position of the terminal galactose using the stannylene procedure. Fucosylation of the sulfated tetrasaccharide was performed using an immobilized fucosyltransferase FucTIII to give the title compound after cleavage.