757959-97-0

Basic information

• Product Name: Norleucine, N-acetyl-4-methyl-
• Synonyms: Norleucine, N-acetyl-4-methyl-
• CAS NO: 757959-97-0
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.24
• Mol File: 757959-97-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Norleucine, N-acetyl-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Norleucine, N-acetyl-4-methyl-(757959-97-0)
• EPA Substance Registry System: Norleucine, N-acetyl-4-methyl-(757959-97-0)

Safety Data

• Hazardous Substances Data: 757959-97-0(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 201230-82-2 carbon monoxide 
• 556-82-1 3-methyl-2-buten-1-ol 
• 105746-99-4 3,10-diethyl-3,6,10-trimethyl-4,9-dioxa-3,10-disiladodecane 
• 115-18-4 2-methyl-3-buten-2-ol 
• 78-79-5 isoprene 

Relevant articles and documents

ON THE CATALYTIC AMIDOCARBONYLATION OF SUBSTITUTED ALLYLIC ALCOHOLS

Substituted allylic alcohols (3-methyl-2-buten-1-ol and 2-methyl-3-buten-2-ol) were isomerized and amidocarbonylated.In addition to the expected product, N-acetylleucine, arising from their rearrengement to 3-methylbutanal and subsequent amidocarbonylation (22percent yield), we isolated two additional products (28percent yield).These were shown by spectroscopic methods and by syntheses, via amidocarbonylations of the respective aldehydes, to be 2-acetamido-5-methylhexanoic acid and 2-acetamido-4-methylhexanoic acid.Their formation is postulated to be the sequential result of (i) dehydration first to form isoprene, (ii) hydroformylation and hydrogenation of isoprene to give 3-methyl-1-pentanal and 4-methyl-1-pentanal, and (iii) aldehyde amidocarbonylation.Treatment of isoprene itself under the same conditions also gave these latter two acetylamino acids.