757964-89-9

Basic information

• Product Name: quinapril hydrochloride acetone solvate
• Synonyms: quinapril hydrochloride acetone solvate
• CAS NO: 757964-89-9
• Molecular Weight: 533.065
• Mol File: 757964-89-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: quinapril hydrochloride acetone solvate(CAS DataBase Reference)
• NIST Chemistry Reference: quinapril hydrochloride acetone solvate(757964-89-9)
• EPA Substance Registry System: quinapril hydrochloride acetone solvate(757964-89-9)

Safety Data

• Hazardous Substances Data: 757964-89-9(Hazardous Substances Data)

Upstream product

• 82586-55-8 quinapril hydrochloride 
• 67-64-1 acetone 

Relevant articles and documents

PREPARATION OF QUINAPRIL HYDROCHLORIDE

Methods and materials for preparing quinapril, its pharmaceutically acceptable salts, including quinapril hydrochloride, are disclosed. The method includes reacting (2S,4S)-2-(4-methyl-2,5-dioxo-oxazolidin-3-yl)-4-phenyl-butyric acid ethyl ester with (3S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid tert-butyl ester to yield quinapril tert-butyl ester, which is subsequently reacted with an acid to yield quinapril or an acid addition salt of quinapril.