75799-18-7

Basic information

• Product Name: Presapogenin CP4
• Synonyms: Presapogenin CP4;Prosapogenin CP4
• CAS NO: 75799-18-7
• Molecular Formula: C₄₆H₇₄O₁₅
• Molecular Weight: 867.07
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 75799-18-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 944.4±65.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3 (20 ºC 760 Torr)
• PKA: 4?+-.0.70(Predicted)
• CAS DataBase Reference: Presapogenin CP4(CAS DataBase Reference)
• NIST Chemistry Reference: Presapogenin CP4(75799-18-7)
• EPA Substance Registry System: Presapogenin CP4(75799-18-7)

Safety Data

• Hazardous Substances Data: 75799-18-7(Hazardous Substances Data)

Usage

General Description

Presapogenin CP4 is a steroidal sapogenin derived from the seeds of fenugreek (Trigonella foenum-graecum). It is primarily used as a starting material for the synthesis of steroidal drugs and hormones. Presapogenin CP4 has been found to exhibit potential anti-inflammatory and anticancer activities, making it a subject of interest for further research and development. Additionally, it has shown antioxidant properties and has been used in the formulation of pharmaceuticals and cosmetics. Overall, Presapogenin CP4 is a versatile chemical with promising therapeutic potential.

Upstream product

• 1352410-47-9 benzyl oleanolate 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1 → 3)-2,4-di-O-acetyl-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside 
• 96315-53-6 Huzhangoside B 
• 72629-77-7 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 76742-94-4 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 76742-94-4 oleanolic acid 3-O-β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->4)-β-D-ribopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 

Downstream Products

• 508-02-1 Oleanolic acid 
• 75026-25-4 β-hederin 
• 28283-45-6 fatsiaside A₁ 
• 35790-95-5 oleanolic acid 3-O-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 28283-45-6 oleanolic acid 3-O-α-L-arabinopyranoside 
• 6014-42-2 L-rhamnose 
• 7296-55-1 L-arabinose 
• 50-69-1 D-ribose 
• 508-02-1 oleanic acid 
• 35790-95-5 oleanic acid 3-O-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 28283-45-6 oleanic acid 3-O-α-L-arabinopyranoside 
• 2460-44-8 β-D-xylopyranoside 
• 508-02-1 oleanolic acid 
• 58-86-6 D-xylose 

Relevant articles and documents

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives

Twenty-six naturally occurring oleanolic acid saponins and their derivatives, 16 of which were synthesized in this study, were preliminarily evaluated against human cancer cells. From SAR studies, the presence of α-l-rhamnosyl residue at the terminal of both C-3 and C-28 position for oleanolic acid bidesmosides was important to enhance cytotoxicity, and introducing more sugar residues at C3-OH of compound 12 with C-28 carboxylic acid is a favorable modification to ameliorate the anticancer activity. Furthermore, α-l-rhamnosyl moiety linked to C2-OH of the first monosaccharide (α-l-alabinose, β-d-xylose, β-d-galactose or β-d-glucose) in C3-OH of oleanolic acid was helpful to improve the cytotoxicity. According to the predicted log P values, lipophilicity of the synthesized saponins was not an important factor for cytotoxicity.

TRITERPENE GLYCOSIDES AND THEIR GENINS FROM Thalictrum foetidum. I. THE STRUCTURE OF FOETOSIDE C

A new glycoside - foetoside C - has been isolated from the epigeal part of Thalictrum foetidum L. and, on the basis of chemical transformations and spectral characteristics its structure has been established as oleanolic acid 28-6)-O-β-D-glucopyranoside> 3-O-3)-O-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside>.

Studies on the constituents of Clematis species. III. On the saponins of the root of Clematis chinensis Osbeck

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