7594-49-2

Basic information

• Product Name: 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL
• Synonyms: 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL;1,1,1,3,3,3-Hexafluoro-2-trichloromethyl-2-propanol;1,1-Bis(trifluoromethyl)-2,2,2-trichloroethanol 97%;1,1-Bis(trifluoromethyl)-2,2,2-trichloroethanol97%;2,2,2-Trichloro-1,1-bis(trifluoromethyl)ethanol, 97%
• CAS NO: 7594-49-2
• Molecular Formula: C₄HCl₃F₆O
• Molecular Weight: 285.4
• Mol File: 7594-49-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 139°C
• Flash Point: 139°C
• Appearance: /
• Density: 1.793g/cm³
• Vapor Pressure: 0.514mmHg at 25°C
• Refractive Index: 1.389
• Storage Temp.: Keep Cold
• Sensitive: Hygroscopic
• BRN: 1841641
• CAS DataBase Reference: 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL(7594-49-2)
• EPA Substance Registry System: 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL(7594-49-2)

Safety Data

• Hazard Codes: Xi
• Statements: 20/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 7594-49-2(Hazardous Substances Data)

Usage

General Description

1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL, also known as Bistrifluoromethyltrichloroethanol, is a chemical compound with the molecular formula C2Cl4F6O. It is a colorless liquid that is commonly used as a solvent in organic synthesis and manufacturing of pharmaceuticals. It is a highly reactive compound and can undergo various chemical reactions, including oxidation and reduction. Bistrifluoromethyltrichloroethanol is also used as a preservative and disinfectant in the healthcare industry due to its antimicrobial properties. However, it is important to handle this compound with caution as it can have toxic effects if not properly managed.

InChI:InChI=1/C4HCl3F6O/c5-2(6,7)1(14,3(8,9)10)4(11,12)13/h14H

Upstream product

• 1515-14-6 1,1,1,3,3,3-hexafluoro-2-methylpropan-2-ol 
• 56-23-5 tetrachloromethane 
• 684-16-2 Hexafluoroacetone 
• 76-03-9 trichloroacetic acid 
• 650-51-1 sodium trichloroacetate 

Downstream Products

• 2378-02-1 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ol 

Relevant articles and documents

REDUCTIVE ADDITION OF POLYCHLOROALKANES TO FLUOROKETONES

-

Structural and solvent effects on rates of solvolysis of secondary alkyl substrates - An update

Rate constants for solvolyses of secondary alkyl tosylates in fluorinated media [including hexafluoropropan-2-ol (HFIP), hexafluoroacetone sesquihydrate, and trichloromethylbis(trifluoromethyl)carbinol] are reported. Rates of solvolysis of 2-adamantyl p-toluenesulfonate in 97% (w/w) HFIP-water at 25°C are neither retarded by the addition of NaOTs nor accelerated greatly by NaClO4). The α-deuterium kinetic isotope effect for solvolyses of 1-(1-adamantyl)ethyl methanesulfonate in 20% acetone-water at 25°C is 1.14. Mechanistic implications of these results are discussed. Copyright