75985-18-1

Basic information

• Product Name: METHYL 5-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE
• Synonyms: METHYL 5-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE
• CAS NO: 75985-18-1
• Molecular Formula: C₇H₉NO₂S
• Molecular Weight: 171.22
• Mol File: 75985-18-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 5-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE(75985-18-1)
• EPA Substance Registry System: METHYL 5-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE(75985-18-1)

Safety Data

• Hazardous Substances Data: 75985-18-1(Hazardous Substances Data)

Usage

General Description

Methyl 5-(aminomethyl)thiophene-2-carboxylate is a chemical compound with the molecular formula C8H9NO2S. It is a derivative of thiophene, a heterocyclic compound containing a five-membered ring of four carbon atoms and one sulfur atom. The presence of the amino group and the ester functional group in this compound makes it useful for the synthesis of various pharmaceuticals and agrochemicals. It has potential applications in the field of medicinal chemistry and drug development due to its ability to serve as a precursor for the preparation of bioactive compounds. Additionally, its unique structure and properties also make it a valuable building block in organic synthesis.

Upstream product

• 503470-01-7 5-azidomethylthiophene-2-carboxylic acid methyl ester 
• 1918-79-2 2-methylthiophene-5-carboxylic acid 
• 19432-69-0 methyl 5-methylthiophene-2-carboxylate 
• 108499-32-7 5-bromomethyl-2-carbomethoxythiophene 

Downstream Products

• 476362-82-0 5-[(3-carboxy-4-hydroxy-benzenesulfonylamino)-methyl]-thiophene-2-carboxylic acid methyl ester 
• 830331-51-6 5-[(4-chloro-benzoylamino)-methyl]-thiophene-2-carboxylic acid methyl ester 
• 830331-52-7 5-[(4-chloro-benzoylamino)-methyl]-thiophene-2-carboxylic acid 
• 476362-84-2 5-[(3-tert-butoxycarbonyl-4-hydroxy-benzenesulfonylamino)methyl]thiophene-2-carboxylic acid 
• 476362-83-1 5-[(3-tert-butoxycarbonyl-4-hydroxy-benzenesulfonylamino)methyl]thiophene-2-carboxylic acid methyl ester 
• 503470-03-9 5-[(5-{1-tert-butoxycarbonylmethyl-2-[5-(2,6-dichloro-phenyl)-oxazol-2-yl]-2-oxo-ethylcarbamoyl}-thiophen-2-ylmethyl)-sulfamoyl]-2-hydroxy-benzoic acid tert-butyl ester 
• 503470-02-8 5-[(5-{1-tert-butoxycarbonylmethyl-2-[5-(2,6-dichloro-phenyl)-oxazol-2-yl]-2-hydroxy-ethylcarbamoyl}-thiophen-2-ylmethyl)-sulfamoyl]-2-hydroxy-benzoic acid tert-butyl ester 
• 1218923-51-3 C₁₄H₁₃NO₄S 

Relevant articles and documents

KCNT1 INHIBITORS AND METHODS OF USE

The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.

Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase

Several lines of evidence support the hypothesis that c-Jun N-terminal kinases (JNKs) play a critical role in a wide range of disease states including cell death (apoptosis)-related and inflammatory disorders (epilepsy, brain, heart and renal ischemia, ne

N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation

Aziridine-2-carboxylic acid derivatives of the formula STR1 wherein X is a carboxyl, nitrile, alkoxycarbonyl or carbamoyl group, and R and R1 are various organic radicals, or pharmacologically acceptable salts thereof, exhibit marked immunostimulant activity, especially in conjunction with added chemotherapeutic agents such as a penicillin, a cephalosporin, a nitrofuran or chloramphenicol. Those compounds are new where X is a cyano group or an alkoxycarbonyl radical and R1 is a hydrogen atom, but R' is not an unsubstituted alkyl radical or an alkyl radical substituted by hydroxyl, alkoxy, dialkylamino, phenyl, 4-chlorophenyl or 4-methoxyphenyl or a vinyl radical substituted by a phenyl or methyl radical, or a cycloalkyl radical, a phenyl a 4-chlorophenyl, a 4-methoxyphenyl, an s-triazinyl or a pyridinyl radical; or where X is a carbamoyl group and R1 is a hydrogen atom, R' is not an unsubstituted cyclohexyl, alkyl or benzyl radical; or where X is a cyano group or an alkoxycarbonyl radical and R1 is a phenyl radical, R' is not an isopropyl, cyclohexyl, phenyl, benzyl or p-chlorobenzyl radical; or where R1 is a methyl radical, R1 is not a benzyl, p-chloro- or p- methoxybenzyl radical.