76-26-6

Basic information

• Product Name: [7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid
• Synonyms: [7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid;(2-Oxo-7,7-dimethylbicyclo[2.2.1]heptane-1-yl)methanesulfonic acid;2-Oxo-7,7-dimethylbicyclo[2.2.1]heptane-1-methanesulfonic acid;2-Oxobornane-10-sulfonic acid;10-Bornanesulfonic acid, 2-oxo-;Einecs 200-949-2
• CAS NO: 76-26-6
• Molecular Formula: C₁₀H₁₆O₄S
• Molecular Weight: 232.29664
• EINECS: 200-949-2
• Mol File: 76-26-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid(76-26-6)
• EPA Substance Registry System: [7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid(76-26-6)

Safety Data

• Hazardous Substances Data: 76-26-6(Hazardous Substances Data)

Usage

Description

[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid, also known as D3-MSA, is a chemical compound derived from camphor with the molecular formula C11H18O4S. It is a white to off-white solid at room temperature, soluble in water and most organic solvents, and is utilized in organic synthesis as a chiral auxiliary and a precursor to other organic compounds.

Uses

Used in Pharmaceutical Industry:
D3-MSA is used as a chiral auxiliary in the production of chiral pharmaceuticals for their specific therapeutic effects. Its unique structure allows for the creation of enantiomerically pure compounds, which is crucial in the development of effective and safe medications.
Used in Agrochemical Industry:
In the agrochemical industry, D3-MSA is used as a precursor to develop crop protection products, such as pesticides and herbicides. Its role in creating chiral compounds aids in enhancing the selectivity and efficiency of these products, reducing potential harm to non-target organisms and the environment.
Used in Research and Development:
D3-MSA is also employed in research and development, particularly in the synthesis of complex organic molecules. Its versatility as a chiral auxiliary makes it a valuable tool for chemists working on the design and synthesis of novel compounds with potential applications in various fields.

Upstream product

• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 

Downstream Products

• 3144-16-9 (1S)-10-camphorsulfonic acid 
• 35963-20-3 (R)-10-camphorsulfonic acid 
• 367522-55-2 7,7-dimethyl-2,3-dioxo-bicyclo[2.2.1]heptane-4-methanesulfonic acid 
• 295788-95-3 8-[2,4-Bis(methoxymethoxy)phenyl]-1,4-dioxaspiro[4.5]dec-7-ene 
• 464-78-8 ketopinic acid 
• 165806-94-0 N-[(4-fluorophenyl)[(4-methylphenyl)sulfonyl]methyl]formamide 
• 10413-17-9 6-phenyltetrahydropyran-2-one 
• 676165-94-9 N-[benzo[1,3]dioxol-5-yl-(toluene-4-sulfonyl)-methyl]-formamide 
• 847448-60-6 4-chloro-2-(tetrahydro-pyran-2-yl)-2H-pyrazolo[3,4-d]pyrimidine 
• 91446-15-0 4-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-d]-pyrimidine 
• 579475-69-7 2-(4-fluoro-2-methylphenyl)-4-piperidinone camphor-10-sulfonate 
• 114214-50-5 3-hydroxy-4-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 368835-52-3 6-Ethyl-3,3-dimethoxy-2-phenyl-2,3,4,5-tetrahydro-pyridine camphorsulfonate 

Relevant articles and documents

Identification of small molecule sulfonic acids as ecto-5'-nucleotidase inhibitors

Ecto-5'-Nucleotidase inhibitors have great potential as anti-tumor agents. We have investigated biochemical properties of human and rat ecto-5'-Nucleotidases and characterized 19 small molecule sulfonic acid derivatives as potential inhibitors of ecto-5'-Nucleotidases. We identified 11 potent inhibitors of human and rat ecto-5'-Nucleotidases and checked their selectivity. Compound 10 (Sodium 2,4-dinitrobenzenesulfonate) with Ki value of 0.66 μM and 19 (N-(4- sulfamoylphenylcarbamothioyl) pivalamide) with Ki value of 0.78 μM were identified as the most potent inhibitors for human and rat ecto-5'-Nucleotidase, respectively. The present compounds have low molecular weights, water solubility and equal potency as compared to the reported inhibitors.

Dibenzonaphthyrones

Dibenzonaphthyrone of formula (I) wherein A1and A2independently of each other are unsubstituted or mono- to tetra-substituted o-C6-C18arylene, with the proviso that formula (I) does not represent a dibenzonaphthyrone of the formula The invention further relates to processes for the preparation thereof, to the use thereof for colouring/pigmenting high-molecular-weight organic material and to substance compositions comprising dibenzonaphthyrones.